ARHGAP25 (Rho GTPase activating protein 25)

2006-10-01  

Identity

HGNC
LOCATION
2p13.3
LOCUSID
ALIAS
HEL-S-308,KAIA0053
FUSION GENES

Other Information

Locus ID:

NCBI: 9938
MIM: 610587
HGNC: 28951
Ensembl: ENSG00000163219

Variants:

dbSNP: 9938
ClinVar: 9938
TCGA: ENSG00000163219
COSMIC: ARHGAP25

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163219ENST00000409030P42331
ENSG00000163219ENST00000409030V9HWC8
ENSG00000163219ENST00000409202P42331
ENSG00000163219ENST00000409220P42331
ENSG00000163219ENST00000463483B7Z8K7
ENSG00000163219ENST00000467265P42331
ENSG00000163219ENST00000473986F8WAV9
ENSG00000163219ENST00000479844C9JB56
ENSG00000163219ENST00000488795F8WDF6
ENSG00000163219ENST00000497079P42331
ENSG00000163219ENST00000497259H7C4P1

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373263272023ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop.2
373263272023ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop.2
361903142022A novel BRET-Based GAP assay reveals phosphorylation-dependent regulation of the RAC-specific GTPase activating protein ARHGAP25.0
362076952022Relationship between the expression of ARHGAP25 and RhoA in non-small cell lung cancer and vasculogenic mimicry.4
361903142022A novel BRET-Based GAP assay reveals phosphorylation-dependent regulation of the RAC-specific GTPase activating protein ARHGAP25.0
362076952022Relationship between the expression of ARHGAP25 and RhoA in non-small cell lung cancer and vasculogenic mimicry.4
339948642021ARHGAP25 Inhibits Pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway.11
339948642021ARHGAP25 Inhibits Pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway.11
312284512019ARHGAP25: A negative regulator of colorectal cancer (CRC) metastasis via the Wnt/β-catenin pathway.12
312284512019ARHGAP25: A negative regulator of colorectal cancer (CRC) metastasis via the Wnt/β-catenin pathway.12
199110112010Mutation of ARHGAP9 in patients with coronary spastic angina.0
199110112010Mutation of ARHGAP9 in patients with coronary spastic angina.0

Citation

Dessen P

ARHGAP25 (Rho GTPase activating protein 25)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43140/arhgap25-(rho-gtpase-activating-protein-25)