Identity
HGNC
LOCATION
1q23.1
LOCUSID
ALIAS
GTRAP48,PDZ-RHOGEF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9826
MIM: 605708
HGNC: 14580
Ensembl: ENSG00000132694
Variants:
dbSNP: 9826
ClinVar: 9826
TCGA: ENSG00000132694
COSMIC: ARHGEF11
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000132694 | ENST00000361409 | O15085 |
| ENSG00000132694 | ENST00000368194 | O15085 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30999786 | 2021 | Epigenetic alteration of Rho guanine nucleotide exchange Factor 11 (ARHGEF11) in cord blood samples in macrosomia exposed to intrauterine hyperglycemia. | 8 |
| 30999786 | 2021 | Epigenetic alteration of Rho guanine nucleotide exchange Factor 11 (ARHGEF11) in cord blood samples in macrosomia exposed to intrauterine hyperglycemia. | 8 |
| 33023908 | 2020 | Gα(s) directly drives PDZ-RhoGEF signaling to Cdc42. | 11 |
| 33122451 | 2020 | ARHGEF11 promotes proliferation and epithelial-mesenchymal transition of hepatocellular carcinoma through activation of β-catenin pathway. | 7 |
| 33023908 | 2020 | Gα(s) directly drives PDZ-RhoGEF signaling to Cdc42. | 11 |
| 33122451 | 2020 | ARHGEF11 promotes proliferation and epithelial-mesenchymal transition of hepatocellular carcinoma through activation of β-catenin pathway. | 7 |
| 30521495 | 2019 | Loss of ARHGEF1 causes a human primary antibody deficiency. | 23 |
| 30521495 | 2019 | Loss of ARHGEF1 causes a human primary antibody deficiency. | 23 |
| 28554271 | 2018 | Genetic variants and clinical relevance associated with gestational diabetes mellitus in Chinese women: a case-control study. | 5 |
| 29486856 | 2018 | ARHGEF11 affecting the placental insulin signaling pathway in fetal macrosomia of normal glucose tolerance pregnant women. | 6 |
| 30219706 | 2018 | PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival. | 10 |
| 28554271 | 2018 | Genetic variants and clinical relevance associated with gestational diabetes mellitus in Chinese women: a case-control study. | 5 |
| 29486856 | 2018 | ARHGEF11 affecting the placental insulin signaling pathway in fetal macrosomia of normal glucose tolerance pregnant women. | 6 |
| 30219706 | 2018 | PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival. | 10 |
| 26522724 | 2016 | Endothelin A receptor drives invadopodia function and cell motility through the β-arrestin/PDZ-RhoGEF pathway in ovarian carcinoma. | 35 |
Citation
Dessen P
ARHGEF11 (Rho guanine nucleotide exchange factor 11)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43145/arhgef11-(rho-guanine-nucleotide-exchange-factor-11)
