Identity
HGNC
LOCATION
13q34
LOCUSID
ALIAS
BETA-PIX,COOL-1,COOL1,Nbla10314,P50,P50BP,P85,P85COOL1,P85SPR,PAK3,PIXB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8874
MIM: 605477
HGNC: 15607
Ensembl: ENSG00000102606
Variants:
dbSNP: 8874
ClinVar: 8874
TCGA: ENSG00000102606
COSMIC: ARHGEF7
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35085554 | 2022 | SRC kinase activator CDCP1 promotes hepatocyte growth factor-induced cell migration/invasion of a subset of breast cancer cells. | 2 |
| 35085554 | 2022 | SRC kinase activator CDCP1 promotes hepatocyte growth factor-induced cell migration/invasion of a subset of breast cancer cells. | 2 |
| 34582006 | 2021 | Beta-Pix-dynamin 2 complex promotes colorectal cancer progression by facilitating membrane dynamics. | 1 |
| 34582006 | 2021 | Beta-Pix-dynamin 2 complex promotes colorectal cancer progression by facilitating membrane dynamics. | 1 |
| 31754215 | 2020 | Indispensable role of STIL in the regulation of cancer cell motility through the lamellipodial accumulation of ARHGEF7-PAK1 complex. | 12 |
| 32188698 | 2020 | ARHGEF7 (β-PIX) Is Required for the Maintenance of Podocyte Architecture and Glomerular Function. | 9 |
| 31754215 | 2020 | Indispensable role of STIL in the regulation of cancer cell motility through the lamellipodial accumulation of ARHGEF7-PAK1 complex. | 12 |
| 32188698 | 2020 | ARHGEF7 (β-PIX) Is Required for the Maintenance of Podocyte Architecture and Glomerular Function. | 9 |
| 31566435 | 2019 | AMPK phosphorylation of the β(1)Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells. | 4 |
| 31566435 | 2019 | AMPK phosphorylation of the β(1)Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells. | 4 |
| 29191942 | 2018 | β-PIX plays an important role in regulation of intestinal epithelial restitution by interacting with GIT1 and Rac1 after wounding. | 7 |
| 29242061 | 2018 | Phosphorylation of Ser-525 in βPix impairs Nox1-activating ability in Caco-2 cells. | 0 |
| 30132516 | 2018 | ARHGEF7 promotes metastasis of colorectal adenocarcinoma by regulating the motility of cancer cells. | 18 |
| 29191942 | 2018 | β-PIX plays an important role in regulation of intestinal epithelial restitution by interacting with GIT1 and Rac1 after wounding. | 7 |
| 29242061 | 2018 | Phosphorylation of Ser-525 in βPix impairs Nox1-activating ability in Caco-2 cells. | 0 |
Citation
Dessen P
ARHGEF7 (Rho guanine nucleotide exchange factor 7)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43153/arhgef7-(rho-guanine-nucleotide-exchange-factor-7)
