BCOR (BCL6 corepressor)

2006-10-01  

Identity

HGNC
LOCATION
Xp11.4
LOCUSID
ALIAS
ANOP2,MAA2,MCOPS2
FUSION GENES

Other Information

Locus ID:

NCBI: 54880
MIM: 300485
HGNC: 20893
Ensembl: ENSG00000183337

Variants:

dbSNP: 54880
ClinVar: 54880
TCGA: ENSG00000183337
COSMIC: BCOR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183337ENST00000342274Q6W2J9
ENSG00000183337ENST00000378444Q6W2J9
ENSG00000183337ENST00000378455Q6W2J9
ENSG00000183337ENST00000397354Q6W2J9
ENSG00000183337ENST00000406200H7BYY2
ENSG00000183337ENST00000412952C9JHP3
ENSG00000183337ENST00000413905H7C2V9
ENSG00000183337ENST00000427012H7C231
ENSG00000183337ENST00000442018H7BZ37
ENSG00000183337ENST00000615339A1A564

Expression (GTEx)

0
5
10
15
20
25
30

References

Pubmed IDYearTitleCitations
108987952000BCoR, a novel corepressor involved in BCL-6 repression.135
169434292006Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets.129
150045582004Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR.88
195783712009BCOR regulates mesenchymal stem cell function by epigenetic mechanisms.86
223879972012A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion.77
220120662011Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype.73
117779152002The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor.55
240476512013BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders.50
182802432008Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer.49
208078882010BCOR as a novel fusion partner of retinoic acid receptor alpha in a t(X;17)(p11;q12) variant of acute promyelocytic leukemia.43

Citation

Dessen P

BCOR (BCL6 corepressor)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43165/bcor-(bcl6-corepressor)