Identity
HGNC
LOCATION
7p13
LOCUSID
ALIAS
CAM2,CAMK2,CAMKB,CaMKIIbeta,MRD54
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 816
MIM: 607707
HGNC: 1461
Ensembl: ENSG00000058404
Variants:
dbSNP: 816
ClinVar: 816
TCGA: ENSG00000058404
COSMIC: CAMK2B
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA248 | NFKB1 | Gene | Pathway | associated | |||
| PA27749 | ELK1 | Gene | Pathway | associated | |||
| PA28212 | FOS | Gene | Pathway | associated | |||
| PA296 | RELA | Gene | Pathway | associated | |||
| PA30006 | JUN | Gene | Pathway | associated | |||
| PA31353 | MYC | Gene | Pathway | associated | |||
| PA31600 | NFKB2 | Gene | Pathway | associated | |||
| PA337 | STAT3 | Gene | Pathway | associated | |||
| PA338 | STAT5A | Gene | Pathway | associated | |||
| PA36042 | SP1 | Gene | Pathway | associated | |||
| PA36183 | STAT1 | Gene | Pathway | associated | |||
| PA36184 | STAT2 | Gene | Pathway | associated | |||
| PA36185 | STAT4 | Gene | Pathway | associated | |||
| PA36186 | STAT5B | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37391113 | 2023 | Understanding the pathogenetic mechanisms underlying altered neuronal function associated with CAMK2B mutations. | 1 |
| 37391113 | 2023 | Understanding the pathogenetic mechanisms underlying altered neuronal function associated with CAMK2B mutations. | 1 |
| 32149607 | 2020 | Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation. | 23 |
| 33019657 | 2020 | CaMKIIβ in Neuronal Development and Plasticity: An Emerging Candidate in Brain Diseases. | 21 |
| 32149607 | 2020 | Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation. | 23 |
| 33019657 | 2020 | CaMKIIβ in Neuronal Development and Plasticity: An Emerging Candidate in Brain Diseases. | 21 |
| 29410121 | 2018 | Calcium/calmodulin-dependent protein kinase II regulation of I(Ks) during sustained β-adrenergic receptor stimulation. | 11 |
| 29410121 | 2018 | Calcium/calmodulin-dependent protein kinase II regulation of I(Ks) during sustained β-adrenergic receptor stimulation. | 11 |
| 28130256 | 2017 | Ca(2+)/calmodulin-dependent protein kinase IIβ and IIδ mediate TGFβ-induced transduction of fibronectin and collagen in human pulmonary fibroblasts. | 10 |
| 29100089 | 2017 | De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability. | 75 |
| 28130256 | 2017 | Ca(2+)/calmodulin-dependent protein kinase IIβ and IIδ mediate TGFβ-induced transduction of fibronectin and collagen in human pulmonary fibroblasts. | 10 |
| 29100089 | 2017 | De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability. | 75 |
| 25045698 | 2014 | Possible inhibitor from traditional Chinese medicine for the β form of calcium-dependent protein kinase type II in the treatment of major depressive disorder. | 1 |
| 25045698 | 2014 | Possible inhibitor from traditional Chinese medicine for the β form of calcium-dependent protein kinase type II in the treatment of major depressive disorder. | 1 |
| 22750393 | 2012 | β-carotene reverses the IL-1β-mediated reduction in paraoxonase-1 expression via induction of the CaMKKII pathway in human endothelial cells. | 5 |
Citation
Dessen P
CAMK2B (calcium/calmodulin dependent protein kinase II beta)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43182/camk2b-(calcium-calmodulin-dependent-protein-kinase-ii-beta)
