Identity
HGNC
LOCATION
7p22.2
LOCUSID
ALIAS
BENTA,BIMP3,CARMA1,IMD11,IMD11A,PPBL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84433
MIM: 607210
HGNC: 16393
Ensembl: ENSG00000198286
Variants:
dbSNP: 84433
ClinVar: 84433
TCGA: ENSG00000198286
COSMIC: CARD11
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198286 | ENST00000355508 | H7BY05 |
| ENSG00000198286 | ENST00000356408 | E2QRC0 |
| ENSG00000198286 | ENST00000396946 | Q9BXL7 |
| ENSG00000198286 | ENST00000396946 | A0A024R854 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38650932 | 2024 | CARD11 regulates the thymic Treg development in an NF-κB-independent manner. | 0 |
| 38650932 | 2024 | CARD11 regulates the thymic Treg development in an NF-κB-independent manner. | 0 |
| 36443613 | 2023 | Very Early Onset Inflammatory Bowel Disease Caused by a Novel Dominant Negative Mutation of Caspase Recruitment Domain 11 (CARD11). | 0 |
| 37086690 | 2023 | CARD11 dominant negative mutation leads to altered human Natural Killer cell homeostasis. | 0 |
| 37385446 | 2023 | A novel variant in caspase recruitment domain family member 11 highlights the variability of clinical manifestations and management in a three generation family. | 0 |
| 37562004 | 2023 | CARD11 gain of function upregulates BCL2A1 expression and promotes resistance to targeted therapies combination in B-cell lymphoma. | 0 |
| 37906628 | 2023 | DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11. | 1 |
| 36443613 | 2023 | Very Early Onset Inflammatory Bowel Disease Caused by a Novel Dominant Negative Mutation of Caspase Recruitment Domain 11 (CARD11). | 0 |
| 37086690 | 2023 | CARD11 dominant negative mutation leads to altered human Natural Killer cell homeostasis. | 0 |
| 37385446 | 2023 | A novel variant in caspase recruitment domain family member 11 highlights the variability of clinical manifestations and management in a three generation family. | 0 |
| 37562004 | 2023 | CARD11 gain of function upregulates BCL2A1 expression and promotes resistance to targeted therapies combination in B-cell lymphoma. | 0 |
| 37906628 | 2023 | DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11. | 1 |
| 36129242 | 2022 | A familial case of B-cell expansion with NF-κB and T-cell anergy caused by a G123D heterozygous missense mutation in the CARD11 gene. | 0 |
| 36334349 | 2022 | Elevated IgE from attenuated CARD11 signaling: lessons from atopic mice and humans. | 2 |
| 36129242 | 2022 | A familial case of B-cell expansion with NF-κB and T-cell anergy caused by a G123D heterozygous missense mutation in the CARD11 gene. | 0 |
Citation
Dessen P
CARD11 (caspase recruitment domain family member 11)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43188
