Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9578
MIM: 614062
HGNC: 1738
Ensembl: ENSG00000198752
Variants:
dbSNP: 9578
ClinVar: 9578
TCGA: ENSG00000198752
COSMIC: CDC42BPB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198752 | ENST00000361246 | Q9Y5S2 |
| ENSG00000198752 | ENST00000361246 | A0A024R6N2 |
| ENSG00000198752 | ENST00000558321 | A0A0U1RRC3 |
| ENSG00000198752 | ENST00000559043 | H0YLY0 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33536006 | 2021 | Helicobacter pylori-induced gastric cancer is orchestrated by MRCKβ-mediated Siah2 phosphorylation. | 3 |
| 33536006 | 2021 | Helicobacter pylori-induced gastric cancer is orchestrated by MRCKβ-mediated Siah2 phosphorylation. | 3 |
| 30667325 | 2020 | The CDC42 effector protein MRCKβ autophosphorylates on Threonine 1108. | 4 |
| 32031333 | 2020 | De novo heterozygous missense and loss-of-function variants in CDC42BPB are associated with a neurodevelopmental phenotype. | 4 |
| 32043305 | 2020 | Sequence variant in the CDC42BPB gene is potentially associated with Mullerian duct anomalies. | 1 |
| 30667325 | 2020 | The CDC42 effector protein MRCKβ autophosphorylates on Threonine 1108. | 4 |
| 32031333 | 2020 | De novo heterozygous missense and loss-of-function variants in CDC42BPB are associated with a neurodevelopmental phenotype. | 4 |
| 32043305 | 2020 | Sequence variant in the CDC42BPB gene is potentially associated with Mullerian duct anomalies. | 1 |
| 29998287 | 2018 | DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies. | 55 |
| 29998287 | 2018 | DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies. | 55 |
| 21240187 | 2011 | Cdc42-dependent formation of the ZO-1/MRCKβ complex at the leading edge controls cell migration. | 40 |
| 21949762 | 2011 | Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion. | 27 |
| 21240187 | 2011 | Cdc42-dependent formation of the ZO-1/MRCKβ complex at the leading edge controls cell migration. | 40 |
| 21949762 | 2011 | Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion. | 27 |
| 20177145 | 2010 | Overexpression and unique rearrangement of VH2 transcripts in immunoglobulin variable heavy chain genes in ankylosing spondylitis patients. | 3 |
Citation
Dessen P
CDC42BPB (CDC42 binding protein kinase beta)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43198/cdc42bpb-(cdc42-binding-protein-kinase-beta)
