Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1018
MIM: 123828
HGNC: 1772
Ensembl: ENSG00000250506
Variants:
dbSNP: 1018
ClinVar: 1018
TCGA: ENSG00000250506
COSMIC: CDK3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000250506 | ENST00000425876 | Q00526 |
| ENSG00000250506 | ENST00000448471 | Q00526 |
| ENSG00000250506 | ENST00000586261 | K7EJ83 |
| ENSG00000250506 | ENST00000588812 | K7ELV5 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33504681 | 2021 | circRNA_141539 can serve as an oncogenic factor in esophageal squamous cell carcinoma by sponging miR-4469 and activating CDK3 gene. | 9 |
| 33504681 | 2021 | circRNA_141539 can serve as an oncogenic factor in esophageal squamous cell carcinoma by sponging miR-4469 and activating CDK3 gene. | 9 |
| 28939591 | 2018 | miR-125a-3p inhibits ERα transactivation and overrides tamoxifen resistance by targeting CDK3 in estrogen receptor-positive breast cancer. | 24 |
| 29344850 | 2018 | HuR facilitates cancer stemness of lung cancer cells via regulating miR-873/CDK3 and miR-125a-3p/CDK3 axis. | 22 |
| 28939591 | 2018 | miR-125a-3p inhibits ERα transactivation and overrides tamoxifen resistance by targeting CDK3 in estrogen receptor-positive breast cancer. | 24 |
| 29344850 | 2018 | HuR facilitates cancer stemness of lung cancer cells via regulating miR-873/CDK3 and miR-125a-3p/CDK3 axis. | 22 |
| 27893713 | 2017 | Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer. | 16 |
| 28108217 | 2017 | CDK3 is a major target of miR-150 in cell proliferation and anti-cancer effect. | 3 |
| 28501005 | 2017 | HuR promotes breast cancer cell proliferation and survival via binding to CDK3 mRNA. | 30 |
| 27893713 | 2017 | Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer. | 16 |
| 28108217 | 2017 | CDK3 is a major target of miR-150 in cell proliferation and anti-cancer effect. | 3 |
| 28501005 | 2017 | HuR promotes breast cancer cell proliferation and survival via binding to CDK3 mRNA. | 30 |
| 26498144 | 2016 | miR-214/199a/199a* cluster levels predict poor survival in hepatocellular carcinoma through interference with cell-cycle regulators. | 15 |
| 26755651 | 2016 | Cdk3-promoted epithelial-mesenchymal transition through activating AP-1 is involved in colorectal cancer metastasis. | 17 |
| 26498144 | 2016 | miR-214/199a/199a* cluster levels predict poor survival in hepatocellular carcinoma through interference with cell-cycle regulators. | 15 |
Citation
Dessen P
CDK3 (cyclin dependent kinase 3)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43201/cdk3
