CDKL1 (cyclin dependent kinase like 1)

2006-10-01  

Identity

HGNC
LOCATION
14q21.3
LOCUSID
ALIAS
KKIALRE,P42
FUSION GENES

Other Information

Locus ID:

NCBI: 8814
MIM: 603441
HGNC: 1781
Ensembl: ENSG00000100490

Variants:

dbSNP: 8814
ClinVar: 8814
TCGA: ENSG00000100490
COSMIC: CDKL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100490ENST00000395834Q00532
ENSG00000100490ENST00000525911H0YCE5
ENSG00000100490ENST00000534267H0YE65

Expression (GTEx)

0
1
2
3
4
5
6
7
8

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
341651792021Egr‑1 inhibits colon cancer cell proliferation, migration and invasion via regulating CDKL1 at the transcriptional level.9
341651792021Egr‑1 inhibits colon cancer cell proliferation, migration and invasion via regulating CDKL1 at the transcriptional level.9
308024952019CDKL1 promotes the chemoresistance of human oral squamous cell carcinoma cells to hydroxycamptothecin.3
308910732019Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.3
308024952019CDKL1 promotes the chemoresistance of human oral squamous cell carcinoma cells to hydroxycamptothecin.3
308910732019Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.3
292627322018Chk1 modulates the interaction between myosin phosphatase targeting protein 1 (MYPT1) and protein phosphatase 1cβ (PP1cβ).7
292627322018Chk1 modulates the interaction between myosin phosphatase targeting protein 1 (MYPT1) and protein phosphatase 1cβ (PP1cβ).7
223696972012A role for Cdkl1 in the development of gastric cancer.10
228044582012Evaluation of cyclin-dependent kinase-like 1 expression in breast cancer tissues and its regulation in cancer cell growth.7
223696972012A role for Cdkl1 in the development of gastric cancer.10
228044582012Evaluation of cyclin-dependent kinase-like 1 expression in breast cancer tissues and its regulation in cancer cell growth.7
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

CDKL1 (cyclin dependent kinase like 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43203/cdkl1-(cyclin-dependent-kinase-like-1)