Identity
HGNC
LOCATION
7p14.3
LOCUSID
ALIAS
ARHGAP3,BCH,CHN2-3,RHOGAP3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1124
MIM: 602857
HGNC: 1944
Ensembl: ENSG00000285162
Variants:
dbSNP: 1124
ClinVar: 1124
TCGA: ENSG00000285162
COSMIC: CHN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000285162 | ENST00000423511 | J3KSU2 |
| ENSG00000285162 | ENST00000644824 | A0A2R8YEI5 |
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406956 | fluorouracil | Chemical | MultilinkAnnotation | associated | 24444404 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37120575 | 2023 | Prenatal phthalate exposure and cord blood DNA methylation. | 1 |
| 37120575 | 2023 | Prenatal phthalate exposure and cord blood DNA methylation. | 1 |
| 34089273 | 2021 | Chemerin regulates formation and function of brown adipose tissue: Ablation results in increased insulin resistance with high fat challenge and aging. | 9 |
| 34089273 | 2021 | Chemerin regulates formation and function of brown adipose tissue: Ablation results in increased insulin resistance with high fat challenge and aging. | 9 |
| 31594917 | 2019 | Integrated genome-wide methylation and expression analyses reveal functional predictors of response to antidepressants. | 23 |
| 31594917 | 2019 | Integrated genome-wide methylation and expression analyses reveal functional predictors of response to antidepressants. | 23 |
| 28160556 | 2017 | Prognostic significance of serum chemerin levels in patients with non-small cell lung cancer. | 25 |
| 28160556 | 2017 | Prognostic significance of serum chemerin levels in patients with non-small cell lung cancer. | 25 |
| 27058424 | 2016 | A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression. | 10 |
| 27058424 | 2016 | A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression. | 10 |
| 26315110 | 2015 | Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility. | 21 |
| 26315110 | 2015 | Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility. | 21 |
| 24854763 | 2014 | Chimerin 2 genetic polymorphisms are associated with non-proliferative diabetic retinopathy in Taiwanese type 2 diabetic patients. | 6 |
| 25057852 | 2014 | Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma. | 24 |
| 24854763 | 2014 | Chimerin 2 genetic polymorphisms are associated with non-proliferative diabetic retinopathy in Taiwanese type 2 diabetic patients. | 6 |
Citation
Dessen P
CHN2 (chimerin 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43212/chn2-(chimerin-2)
