Identity
HGNC
LOCATION
17q21.33
LOCUSID
ALIAS
MMS4L,SLX2A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 146956
MIM: 610885
HGNC: 24965
Ensembl: ENSG00000154920
Variants:
dbSNP: 146956
ClinVar: 146956
TCGA: ENSG00000154920
COSMIC: EME1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33298441 | 2020 | Mus81-Eme1-dependent aberrant processing of DNA replication intermediates in mitosis impairs genome integrity. | 19 |
| 33298441 | 2020 | Mus81-Eme1-dependent aberrant processing of DNA replication intermediates in mitosis impairs genome integrity. | 19 |
| 29850896 | 2018 | Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress. | 13 |
| 29850896 | 2018 | Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress. | 13 |
| 28813668 | 2017 | Subnuclear Relocalization of Structure-Specific Endonucleases in Response to DNA Damage. | 13 |
| 28813668 | 2017 | Subnuclear Relocalization of Structure-Specific Endonucleases in Response to DNA Damage. | 13 |
| 27354282 | 2016 | SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr). | 26 |
| 27354282 | 2016 | SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr). | 26 |
| 24733841 | 2014 | Crystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substrates. | 19 |
| 24733841 | 2014 | Crystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substrates. | 19 |
| 24076221 | 2013 | Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells. | 167 |
| 24076221 | 2013 | Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells. | 167 |
| 21858151 | 2011 | Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation. | 64 |
| 21859861 | 2011 | Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease. | 104 |
| 21858151 | 2011 | Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation. | 64 |
Citation
Dessen P
EME1 (essential meiotic structure-specific endonuclease 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43242/eme1-(essential-meiotic-structure-specific-endonuclease-1)
