EPHA10 (EPH receptor A10)

2006-10-01  

Identity

HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 284656
MIM: 611123
HGNC: 19987
Ensembl: ENSG00000183317

Variants:

dbSNP: 284656
ClinVar: 284656
TCGA: ENSG00000183317
COSMIC: EPHA10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183317ENST00000319637Q5JZY3
ENSG00000183317ENST00000373048Q5JZY3
ENSG00000183317ENST00000427468J3KQG3
ENSG00000183317ENST00000432874H0YER4
ENSG00000183317ENST00000437645H0YD12
ENSG00000183317ENST00000525749H0YEP6
ENSG00000183317ENST00000534097H0YCC9
ENSG00000183317ENST00000540011F5GWI2

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
EPH-Ephrin signalingREACTOMER-HSA-2682334
EPHA-mediated growth cone collapseREACTOMER-HSA-3928663
EPH-ephrin mediated repulsion of cellsREACTOMER-HSA-3928665

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
360488502023A non-coding variant in 5' untranslated region drove up-regulation of pseudo-kinase EPHA10 and caused non-syndromic hearing loss in humans.1
360488502023A non-coding variant in 5' untranslated region drove up-regulation of pseudo-kinase EPHA10 and caused non-syndromic hearing loss in humans.1
358395642022EphA10 drives tumor progression and immune evasion by regulating the MAPK/ERK cascade in lung adenocarcinoma.4
358395642022EphA10 drives tumor progression and immune evasion by regulating the MAPK/ERK cascade in lung adenocarcinoma.4
334367722021Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells.7
339903692021Coexpression of EphA10 and Gli3 promotes breast cancer cell proliferation, invasion and migration.2
334367722021Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells.7
339903692021Coexpression of EphA10 and Gli3 promotes breast cancer cell proliferation, invasion and migration.2
320532752020Cataloguing the dead: breathing new life into pseudokinase research.14
320532752020Cataloguing the dead: breathing new life into pseudokinase research.14
284272232017Isoform expression patterns of EPHA10 protein mediate breast cancer progression by regulating the E-Cadherin and β-catenin complex.8
284272232017Isoform expression patterns of EPHA10 protein mediate breast cancer progression by regulating the E-Cadherin and β-catenin complex.8
275666542016EPHA7 and EPHA10 Physically Interact and Differentially Co-localize in Normal Breast and Breast Carcinoma Cell Lines, and the Co-localization Pattern Is Altered in EPHB6-expressing MDA-MB-231 Cells.9
275666542016EPHA7 and EPHA10 Physically Interact and Differentially Co-localize in Normal Breast and Breast Carcinoma Cell Lines, and the Co-localization Pattern Is Altered in EPHB6-expressing MDA-MB-231 Cells.9
249246292014Eph receptor A10 has a potential as a target for a prostate cancer therapy.15

Citation

Dessen P

EPHA10 (EPH receptor A10)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43243/epha10-(eph-receptor-a10)