ERAS (ES cell expressed Ras)

2006-10-01 Affiliation

Identity

HGNC

ERAS

LOCATION

Xp11.23

LOCUSID

3266

ALIAS

HRAS2,HRASP

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 3266
MIM: 300437
HGNC: 5174
Ensembl: ENSG00000187682

Variants:

dbSNP: 3266
ClinVar: 3266
TCGA: ENSG00000187682
COSMIC: ERAS

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000187682	ENST00000338270	Q7Z444
ENSG00000187682	ENST00000636362	Q7Z444

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
12774123	2003	Role of ERas in promoting tumour-like properties in mouse embryonic stem cells.	109
25624498	2015	BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model.	52
22875024	2012	Functional genomics identifies drivers of medulloblastoma dissemination.	17
20566745	2010	Role of ES cell-expressed Ras (ERas) in tumorigenicity of gastric cancer.	13
16081664	2005	Human ERas gene has an upstream premature polyadenylation signal that results in a truncated, noncoding transcript.	10
18174262	2008	A novel rasH2 mouse carcinogenesis model that is highly susceptible to 4-NQO-induced tongue and esophageal carcinogenesis is useful for preclinical chemoprevention studies.	9
19528480	2009	Expression of ERas oncogene in gastric carcinoma.	9
19787253	2009	Epigenetic regulation of the embryonic oncogene ERas in gastric cancer cells.	9
20811723	2010	Resistance to chemotherapeutic agents and promotion of transforming activity mediated by embryonic stem cell-expressed Ras (ERas) signal in neuroblastoma cells.	9
23612786	2013	Role of the ERas gene in gastric cancer cells.	5

Citation

Dessen P

ERAS (ES cell expressed Ras)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43246/eras-(es-cell-expressed-ras)