FASTK (Fas activated serine/threonine kinase)

2006-10-01 Affiliation

Identity

HGNC

FASTK

LOCATION

7q36.1

LOCUSID

10922

ALIAS

FAST

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 10922
MIM: 606965
HGNC: 24676
Ensembl: ENSG00000164896

Variants:

dbSNP: 10922
ClinVar: 10922
TCGA: ENSG00000164896
COSMIC: FASTK

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000164896	ENST00000297532	Q14296
ENSG00000164896	ENST00000297532	A0A090N8Z7
ENSG00000164896	ENST00000353841	Q14296
ENSG00000164896	ENST00000353841	A0A090N8I0
ENSG00000164896	ENST00000482571	Q14296
ENSG00000164896	ENST00000540185	G3V1R6

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
38253932	2024	Accuracy of FAST in detecting intraabdominal bleeding in major trauma with pelvic and/or acetabular fractures: a retrospective cohort study.	0
38253932	2024	Accuracy of FAST in detecting intraabdominal bleeding in major trauma with pelvic and/or acetabular fractures: a retrospective cohort study.	0
34768773	2021	Systematic Analysis of FASTK Gene Family Alterations in Cancer.	6
34768773	2021	Systematic Analysis of FASTK Gene Family Alterations in Cancer.	6
25704814	2015	A mitochondria-specific isoform of FASTK is present in mitochondrial RNA granules and regulates gene expression and function.	50
25704814	2015	A mitochondria-specific isoform of FASTK is present in mitochondrial RNA granules and regulates gene expression and function.	50
24013584	2013	miR-106a-5p inhibits the proliferation and migration of astrocytoma cells and promotes apoptosis by targeting FASTK.	35
24013584	2013	miR-106a-5p inhibits the proliferation and migration of astrocytoma cells and promotes apoptosis by targeting FASTK.	35
20363972	2010	Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation.	8
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
20363972	2010	Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation.	8
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
19058789	2009	A common variant in DRD3 receptor is associated with autism spectrum disorder.	31
19058789	2009	A common variant in DRD3 receptor is associated with autism spectrum disorder.	31
17135269	2007	Fas-activated serine/threonine kinase (FAST K) synergizes with TIA-1/TIAR proteins to regulate Fas alternative splicing.	46

Citation

Dessen P

FASTK (Fas activated serine/threonine kinase)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43254/fastk-(fas-activated-serine-threonine-kinase)