FCHSD2 (FCH and double SH3 domains 2)

2006-10-01  

Identity

HGNC
FCHSD2
LOCATION
11q13.4
LOCUSID
9873
ALIAS
NWK,NWK1,SH3MD3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9873
MIM: 617556
HGNC: 29114
Ensembl: ENSG00000137478

Variants:

dbSNP: 9873
ClinVar: 9873
TCGA: ENSG00000137478
COSMIC: FCHSD2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137478ENST00000311172O94868
ENSG00000137478ENST00000311172A0A024R5H2
ENSG00000137478ENST00000409263B8ZZW8
ENSG00000137478ENST00000409314E9PG19
ENSG00000137478ENST00000409418O94868
ENSG00000137478ENST00000409853O94868
ENSG00000137478ENST00000422375C9JM66
ENSG00000137478ENST00000432043H0Y6M2
ENSG00000137478ENST00000458644E7ENZ2
ENSG00000137478ENST00000543644H0YG35

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
266633012016Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.15
281992112017Endocytosis and membrane receptor internalization: implication of F-BAR protein Carom.7
229020562012FCHSD2 predicts response to chemotherapy in acute myeloid leukemia patients.5
302496602018Role for ERK1/2-dependent activation of FCHSD2 in cancer cell-selective regulation of clathrin-mediated endocytosis.3

Citation

Dessen P

FCHSD2 (FCH and double SH3 domains 2)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43258/fchsd2-(fch-and-double-sh3-domains-2)