Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10672
MIM: 604406
HGNC: 4381
Ensembl: ENSG00000120063
Variants:
dbSNP: 10672
ClinVar: 10672
TCGA: ENSG00000120063
COSMIC: GNA13
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000120063 | ENST00000439174 | Q14344 |
| ENSG00000120063 | ENST00000439174 | A0A024R8M0 |
| ENSG00000120063 | ENST00000541118 | Q14344 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA131285527 | oxaliplatin | Chemical | MultilinkAnnotation | associated | 24444404 | ||
| PA27946 | F2R | Gene | Pathway | associated | 20938371 | ||
| PA27949 | F2RL3 | Gene | Pathway | associated | 20938371 | ||
| PA32868 | P2RY1 | Gene | Pathway | associated | 20938371 | ||
| PA33384 | PLCB1 | Gene | Pathway | associated | 20938371 | ||
| PA33393 | PLCG2 | Gene | Pathway | associated | 20938371 | ||
| PA348 | TBXA2R | Gene | Pathway | associated | 20938371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38357893 | 2024 | The lncRNA TRG-AS1 promotes the growth of colorectal cancer cells through the regulation of P2RY10/GNA13. | 0 |
| 38357893 | 2024 | The lncRNA TRG-AS1 promotes the growth of colorectal cancer cells through the regulation of P2RY10/GNA13. | 0 |
| 36442589 | 2023 | Overexpressed Gα13 activates serum response factor through stoichiometric imbalance with Gβγ and mislocalization to the cytoplasm. | 0 |
| 36442589 | 2023 | Overexpressed Gα13 activates serum response factor through stoichiometric imbalance with Gβγ and mislocalization to the cytoplasm. | 0 |
| 33423045 | 2021 | GNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner. | 10 |
| 33423045 | 2021 | GNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner. | 10 |
| 31676466 | 2020 | The role of genes affected by human evolution marker GNA13 in schizophrenia. | 2 |
| 32330601 | 2020 | Divergent C-terminal motifs in Gα12 and Gα13 provide distinct mechanisms of effector binding and SRF activation. | 2 |
| 32778842 | 2020 | G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3. | 23 |
| 33023908 | 2020 | Gα(s) directly drives PDZ-RhoGEF signaling to Cdc42. | 11 |
| 33109615 | 2020 | Naturally occurring hotspot cancer mutations in Gα(13) promote oncogenic signaling. | 13 |
| 31676466 | 2020 | The role of genes affected by human evolution marker GNA13 in schizophrenia. | 2 |
| 32330601 | 2020 | Divergent C-terminal motifs in Gα12 and Gα13 provide distinct mechanisms of effector binding and SRF activation. | 2 |
| 32778842 | 2020 | G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3. | 23 |
| 33023908 | 2020 | Gα(s) directly drives PDZ-RhoGEF signaling to Cdc42. | 11 |
Citation
Dessen P
GNA13 (G protein subunit alpha 13)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43273/gna13-(g-protein-subunit-alpha-13)
