Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2769
MIM: 139314
HGNC: 4383
Ensembl: ENSG00000060558
Variants:
dbSNP: 2769
ClinVar: 2769
TCGA: ENSG00000060558
COSMIC: GNA15
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000060558 | ENST00000262958 | P30679 |
| ENSG00000060558 | ENST00000592455 | K7EP74 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA27946 | F2R | Gene | Pathway | associated | 20938371 | ||
| PA27949 | F2RL3 | Gene | Pathway | associated | 20938371 | ||
| PA32868 | P2RY1 | Gene | Pathway | associated | 20938371 | ||
| PA33384 | PLCB1 | Gene | Pathway | associated | 20938371 | ||
| PA33393 | PLCG2 | Gene | Pathway | associated | 20938371 | ||
| PA348 | TBXA2R | Gene | Pathway | associated | 20938371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36642112 | 2023 | Exosomal miR-211-5p regulates glucose metabolism, pyroptosis, and immune microenvironment of melanoma through GNA15. | 8 |
| 36642112 | 2023 | Exosomal miR-211-5p regulates glucose metabolism, pyroptosis, and immune microenvironment of melanoma through GNA15. | 8 |
| 25701539 | 2015 | GNA15 expression in small intestinal neuroendocrine neoplasia: functional and signalling pathway analyses. | 7 |
| 25701539 | 2015 | GNA15 expression in small intestinal neuroendocrine neoplasia: functional and signalling pathway analyses. | 7 |
| 23200847 | 2013 | Ectopic expression of the heterotrimeric G15 protein in pancreatic carcinoma and its potential in cancer signal transduction. | 4 |
| 24204697 | 2013 | Heterotrimeric G-protein, Gα16, is a critical downstream effector of non-canonical Wnt signaling and a potent inhibitor of transformed cell growth in non small cell lung cancer. | 9 |
| 23200847 | 2013 | Ectopic expression of the heterotrimeric G15 protein in pancreatic carcinoma and its potential in cancer signal transduction. | 4 |
| 24204697 | 2013 | Heterotrimeric G-protein, Gα16, is a critical downstream effector of non-canonical Wnt signaling and a potent inhibitor of transformed cell growth in non small cell lung cancer. | 9 |
| 22227248 | 2012 | Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq. | 17 |
| 22227248 | 2012 | Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq. | 17 |
| 21486497 | 2011 | Gα16 interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signaling. | 3 |
| 21486497 | 2011 | Gα16 interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signaling. | 3 |
| 20150327 | 2010 | The puzzling uniqueness of the heterotrimeric G15 protein and its potential beyond hematopoiesis. | 15 |
| 20150327 | 2010 | The puzzling uniqueness of the heterotrimeric G15 protein and its potential beyond hematopoiesis. | 15 |
| 19275934 | 2009 | Heterotrimeric G proteins demonstrate differential sensitivity to beta-arrestin dependent desensitization. | 4 |
Citation
Dessen P
GNA15 (G protein subunit alpha 15)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43275/gna15-(g-protein-subunit-alpha-15)
