Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2770
MIM: 139310
HGNC: 4384
Ensembl: ENSG00000127955
Variants:
dbSNP: 2770
ClinVar: 2770
TCGA: ENSG00000127955
COSMIC: GNAI1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA134971947 | P2RY12 | Gene | Pathway | associated | 20938371 | ||
| PA164741137 | ADCY3 | Gene | Pathway | associated | 20938371 | ||
| PA192 | HTR1A | Gene | Pathway | associated | 19741567 | ||
| PA24560 | ADCY1 | Gene | Pathway | associated | 19741567 | ||
| PA24561 | ADCY2 | Gene | Pathway | associated | 19741567 | ||
| PA24562 | ADCY4 | Gene | Pathway | associated | |||
| PA24563 | ADCY5 | Gene | Pathway | associated | |||
| PA27 | ADCY6 | Gene | Pathway | associated | |||
| PA28 | ADCY7 | Gene | Pathway | associated | |||
| PA29 | ADCY8 | Gene | Pathway | associated | |||
| PA29549 | HTR1B | Gene | Pathway | associated | 19741567 | ||
| PA29550 | HTR1D | Gene | Pathway | associated | 19741567 | ||
| PA29552 | HTR1E | Gene | Pathway | associated | 19741567 | ||
| PA29553 | HTR1F | Gene | Pathway | associated | 19741567 | ||
| PA30 | ADCY9 | Gene | Pathway | associated | |||
| PA34361 | RGS1 | Gene | Pathway | associated | |||
| PA39 | ADRB2 | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34860335 | 2023 | Candidate Gene of NOS3, MMP3, AGT, and AGT1R and Pathway Analyses for Platelet Reactivity and Clinical Outcomes of Repeat Revascularization After First PCI in Chinese Patients. | 0 |
| 37153740 | 2023 | Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis. | 12 |
| 38049415 | 2023 | Overexpressed Gαi1 exerts pro-tumorigenic activity in nasopharyngeal carcinoma. | 0 |
| 34860335 | 2023 | Candidate Gene of NOS3, MMP3, AGT, and AGT1R and Pathway Analyses for Platelet Reactivity and Clinical Outcomes of Repeat Revascularization After First PCI in Chinese Patients. | 0 |
| 37153740 | 2023 | Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis. | 12 |
| 38049415 | 2023 | Overexpressed Gαi1 exerts pro-tumorigenic activity in nasopharyngeal carcinoma. | 0 |
| 33493164 | 2021 | Gαi1 inhibition mechanism of ATP-bound adenylyl cyclase type 5. | 4 |
| 33785921 | 2021 | Feeling at home: Structure of the NTSR1-G(i) complex in a lipid environment. | 0 |
| 33958720 | 2021 | LncRNA PINK1-AS promotes Gαi1-driven gastric cancer tumorigenesis by sponging microRNA-200a. | 20 |
| 33493164 | 2021 | Gαi1 inhibition mechanism of ATP-bound adenylyl cyclase type 5. | 4 |
| 33785921 | 2021 | Feeling at home: Structure of the NTSR1-G(i) complex in a lipid environment. | 0 |
| 33958720 | 2021 | LncRNA PINK1-AS promotes Gαi1-driven gastric cancer tumorigenesis by sponging microRNA-200a. | 20 |
| 31936673 | 2020 | Preferential Coupling of Dopamine D(2S) and D(2L) Receptor Isoforms with G(i1) and G(i2) Proteins-In Silico Study. | 10 |
| 32126208 | 2020 | Structures of Gα Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms. | 13 |
| 32193322 | 2020 | Structural basis of G(s) and G(i) recognition by the human glucagon receptor. | 73 |
Citation
Dessen P
GNAI1 (G protein subunit alpha i1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43276/gnai1-(g-protein-subunit-alpha-i1)
