Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10750
MIM: 604330
HGNC: 4562
Ensembl: ENSG00000154016
Variants:
dbSNP: 10750
ClinVar: 10750
TCGA: ENSG00000154016
COSMIC: GRAP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000154016 | ENST00000284154 | Q13588 |
| ENSG00000154016 | ENST00000395635 | A8MW78 |
| ENSG00000154016 | ENST00000573099 | I3L2P9 |
| ENSG00000154016 | ENST00000583020 | J3QRP9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by SCF-KIT | REACTOME | R-HSA-1433557 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35972996 | 2022 | m(6)A Modification-mediated GRAP Regulates Vascular Remodeling in Hypoxic Pulmonary Hypertension. | 6 |
| 35972996 | 2022 | m(6)A Modification-mediated GRAP Regulates Vascular Remodeling in Hypoxic Pulmonary Hypertension. | 6 |
| 30610177 | 2019 | Dysfunction of GRAP, encoding the GRB2-related adaptor protein, is linked to sensorineural hearing loss. | 6 |
| 30610177 | 2019 | Dysfunction of GRAP, encoding the GRB2-related adaptor protein, is linked to sensorineural hearing loss. | 6 |
| 29364705 | 2018 | miR-654-5p Targets GRAP to Promote Proliferation, Metastasis, and Chemoresistance of Oral Squamous Cell Carcinoma Through Ras/MAPK Signaling. | 39 |
| 29364705 | 2018 | miR-654-5p Targets GRAP to Promote Proliferation, Metastasis, and Chemoresistance of Oral Squamous Cell Carcinoma Through Ras/MAPK Signaling. | 39 |
| 19836472 | 2010 | Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling. | 14 |
| 19836472 | 2010 | Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling. | 14 |
| 18295596 | 2008 | CD28 and Grb-2, relative to Gads or Grap, preferentially co-operate with Vav1 in the activation of NFAT/AP-1 transcription. | 8 |
| 18295596 | 2008 | CD28 and Grb-2, relative to Gads or Grap, preferentially co-operate with Vav1 in the activation of NFAT/AP-1 transcription. | 8 |
| 15174222 | 2004 | Detection of Grb-2-related adaptor protein gene (GRAP) and peptide molecule in salivary glands of MRL/lpr mice and patients with Sjögren's syndrome. | 1 |
| 15174222 | 2004 | Detection of Grb-2-related adaptor protein gene (GRAP) and peptide molecule in salivary glands of MRL/lpr mice and patients with Sjögren's syndrome. | 1 |
| 12491092 | 2003 | Polymorphisms of four bone mineral density candidate genes in Chinese populations and comparison with other populations of different ethnicity. | 9 |
| 12491092 | 2003 | Polymorphisms of four bone mineral density candidate genes in Chinese populations and comparison with other populations of different ethnicity. | 9 |
Citation
Dessen P
GRAP (GRB2 related adaptor protein)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43299/grap-(grb2-related-adaptor-protein)
