Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 30811
MIM: 606532
HGNC: 13326
Ensembl: ENSG00000142149
Variants:
dbSNP: 30811
ClinVar: 30811
TCGA: ENSG00000142149
COSMIC: HUNK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000142149 | ENST00000270112 | P57058 |
| ENSG00000142149 | ENST00000430354 | H7C3H0 |
| ENSG00000142149 | ENST00000439107 | H7C2X2 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38071109 | 2024 | HUNK inhibits cargo uptake and lysosomal traffic in the caveolar pathway via the AGAP3/ARF6. | 0 |
| 38071109 | 2024 | HUNK inhibits cargo uptake and lysosomal traffic in the caveolar pathway via the AGAP3/ARF6. | 0 |
| 37193711 | 2023 | HUNK inhibits epithelial-mesenchymal transition of CRC via direct phosphorylation of GEF-H1 and activating RhoA/LIMK-1/CFL-1. | 1 |
| 37193711 | 2023 | HUNK inhibits epithelial-mesenchymal transition of CRC via direct phosphorylation of GEF-H1 and activating RhoA/LIMK-1/CFL-1. | 1 |
| 31597954 | 2020 | HUNK phosphorylates EGFR to regulate breast cancer metastasis. | 18 |
| 31597954 | 2020 | HUNK phosphorylates EGFR to regulate breast cancer metastasis. | 18 |
| 31752345 | 2019 | HUNK Phosphorylates Rubicon to Support Autophagy. | 7 |
| 31752345 | 2019 | HUNK Phosphorylates Rubicon to Support Autophagy. | 7 |
| 28189783 | 2017 | Hormonally up-regulated neu-associated kinase: A novel target for breast cancer progression. | 4 |
| 28189783 | 2017 | Hormonally up-regulated neu-associated kinase: A novel target for breast cancer progression. | 4 |
| 25515931 | 2015 | Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors. | 15 |
| 25515931 | 2015 | Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors. | 15 |
| 21393859 | 2011 | Hunk is required for HER2/neu-induced mammary tumorigenesis. | 20 |
| 21393859 | 2011 | Hunk is required for HER2/neu-induced mammary tumorigenesis. | 20 |
| 20133759 | 2010 | HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1. | 23 |
Citation
Dessen P
HUNK (hormonally up-regulated Neu-associated kinase)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43311/hunk-(hormonally-up-regulated-neu-associated-kinase)
