CARD18 (caspase recruitment domain family member 18)

2006-10-01  

Identity

HGNC
LOCATION
11q22.3
LOCUSID
ALIAS
ICEBERG,UNQ5804,pseudo-ICE

Other Information

Locus ID:

NCBI: 59082
MIM: 605354
HGNC: 28861
Ensembl: ENSG00000255501

Variants:

dbSNP: 59082
ClinVar: 59082
TCGA: ENSG00000255501
COSMIC: CARD18

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000255501ENST00000526823G5EA35
ENSG00000255501ENST00000530950P57730
ENSG00000255501ENST00000532895G5EA35
ENSG00000255501ENST00000649856G5EA35

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
NOD-like receptor signaling pathwayKEGGko04621
NOD-like receptor signaling pathwayKEGGhsa04621

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
210480312011Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.5
270233782016Keratinocytes express functional CARD18, a negative regulator of inflammasome activation, and its altered expression in psoriasis may contribute to disease pathogenesis.4
285066832017The caspase-1 inhibitor CARD18 is specifically expressed during late differentiation of keratinocytes and its expression is lost in lichen planus.1
239484152013[The expression of CARD18 in apoptin-transfected gastric cancer cells and gastric adenocarcinoma tissues].0

Citation

Dessen P

CARD18 (caspase recruitment domain family member 18)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43312/card18-(caspase-recruitment-domain-family-member-18)