Identity
HGNC
LOCATION
6q23.3
LOCUSID
ALIAS
A7322,BIG3,C6orf92,KIAA1244,PPP1R33,dJ171N11.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57221
MIM: 617411
HGNC: 21213
Ensembl: ENSG00000112379
Variants:
dbSNP: 57221
ClinVar: 57221
TCGA: ENSG00000112379
COSMIC: ARFGEF3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000112379 | ENST00000251691 | Q5TH69 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34363714 | 2021 | The survival and proliferation of osteosarcoma cells are dependent on the mitochondrial BIG3-PHB2 complex formation. | 8 |
| 34363714 | 2021 | The survival and proliferation of osteosarcoma cells are dependent on the mitochondrial BIG3-PHB2 complex formation. | 8 |
| 31421830 | 2019 | Biophysical characterization of the breast cancer-related BIG3-PHB2 interaction: Effect of non-conserved loop region of BIG3 on the structure and the interaction. | 2 |
| 31421830 | 2019 | Biophysical characterization of the breast cancer-related BIG3-PHB2 interaction: Effect of non-conserved loop region of BIG3 on the structure and the interaction. | 2 |
| 24997568 | 2014 | Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (BIG3) is predicted to interact with its partner through an ARM-type α-helical structure. | 4 |
| 24997568 | 2014 | Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (BIG3) is predicted to interact with its partner through an ARM-type α-helical structure. | 4 |
Citation
Dessen P
ARFGEF3 (ARFGEF family member 3)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43331/arfgef3-(arfgef-family-member-3)
