Identity
HGNC
LOCATION
19p13.13
LOCUSID
ALIAS
MCCCHCM,SAST
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22983
MIM: 612256
HGNC: 19034
Ensembl: ENSG00000105613
Variants:
dbSNP: 22983
ClinVar: 22983
TCGA: ENSG00000105613
COSMIC: MAST1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000105613 | ENST00000251472 | Q9Y2H9 |
| ENSG00000105613 | ENST00000588379 | K7EJZ9 |
| ENSG00000105613 | ENST00000590204 | K7EJI7 |
| ENSG00000105613 | ENST00000591495 | K7EME4 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38331765 | 2024 | CircMAST1 inhibits cervical cancer progression by hindering the N4-acetylcytidine modification of YAP mRNA. | 1 |
| 38498222 | 2024 | USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells. | 0 |
| 38331765 | 2024 | CircMAST1 inhibits cervical cancer progression by hindering the N4-acetylcytidine modification of YAP mRNA. | 1 |
| 38498222 | 2024 | USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells. | 0 |
| 34400618 | 2021 | Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1. | 22 |
| 34774870 | 2021 | Mast1 mediates radiation-induced gastric injury via the P38 MAPK pathway. | 4 |
| 34400618 | 2021 | Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1. | 22 |
| 34774870 | 2021 | Mast1 mediates radiation-induced gastric injury via the P38 MAPK pathway. | 4 |
| 31721002 | 2020 | Evaluating the Role of MAST1 as an Intellectual Disability Disease Gene: Identification of a Novel De Novo Variant in a Patient with Developmental Disabilities. | 9 |
| 32291963 | 2020 | MAST1 modulates neuronal differentiation and cell cycle exit via P27 in neuroblastoma cells. | 2 |
| 31721002 | 2020 | Evaluating the Role of MAST1 as an Intellectual Disability Disease Gene: Identification of a Novel De Novo Variant in a Patient with Developmental Disabilities. | 9 |
| 32291963 | 2020 | MAST1 modulates neuronal differentiation and cell cycle exit via P27 in neuroblastoma cells. | 2 |
| 31449053 | 2019 | Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation. | 21 |
| 31449053 | 2019 | Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation. | 21 |
| 30449657 | 2018 | Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. | 17 |
Citation
Dessen P
MAST1 (microtubule associated serine/threonine kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43353/mast1-(microtubule-associated-serine-threonine-kinase-1)
