Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 85366
MIM: 606566
HGNC: 16243
Ensembl: ENSG00000101306
Variants:
dbSNP: 85366
ClinVar: 85366
TCGA: ENSG00000101306
COSMIC: MYLK2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101306 | ENST00000375985 | Q9H1R3 |
| ENSG00000101306 | ENST00000375994 | Q9H1R3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33455984 | 2021 | FLNC and MYLK2 Gene Mutations in a Chinese Family with Different Phenotypes of Cardiomyopathy. | 3 |
| 34000008 | 2021 | A novel tumor suppressor role of myosin light chain kinase splice variants through downregulation of the TEAD4/CD44 axis. | 3 |
| 33455984 | 2021 | FLNC and MYLK2 Gene Mutations in a Chinese Family with Different Phenotypes of Cardiomyopathy. | 3 |
| 34000008 | 2021 | A novel tumor suppressor role of myosin light chain kinase splice variants through downregulation of the TEAD4/CD44 axis. | 3 |
| 25825456 | 2016 | Dual LQT1 and HCM phenotypes associated with tetrad heterozygous mutations in KCNQ1, MYH7, MYLK2, and TMEM70 genes in a three-generation Chinese family. | 13 |
| 25825456 | 2016 | Dual LQT1 and HCM phenotypes associated with tetrad heterozygous mutations in KCNQ1, MYH7, MYLK2, and TMEM70 genes in a three-generation Chinese family. | 13 |
| 19667195 | 2009 | Single-molecule force spectroscopy distinguishes target binding modes of calmodulin. | 12 |
| 19667195 | 2009 | Single-molecule force spectroscopy distinguishes target binding modes of calmodulin. | 12 |
| 18828194 | 2008 | Variation in the myosin light chain kinase gene is associated with development of acute lung injury after major trauma. | 62 |
| 18828194 | 2008 | Variation in the myosin light chain kinase gene is associated with development of acute lung injury after major trauma. | 62 |
| 16448786 | 2006 | Mutational analysis of the kinase domain of MYLK2 gene in common human cancers. | 6 |
| 16448786 | 2006 | Mutational analysis of the kinase domain of MYLK2 gene in common human cancers. | 6 |
| 16448786 | 2006 | Mutational analysis of the kinase domain of MYLK2 gene in common human cancers. | 6 |
| 16448786 | 2006 | Mutational analysis of the kinase domain of MYLK2 gene in common human cancers. | 6 |
| 14500714 | 2003 | P2X1-mediated ERK2 activation amplifies the collagen-induced platelet secretion by enhancing myosin light chain kinase activation. | 14 |
Citation
Dessen P
MYLK2 (myosin light chain kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43365/mylk2-(myosin-light-chain-kinase-2)
