Identity
HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
AIADK,CARD7,CIDED,CLR17.1,DEFCAP,DEFCAP-L/S,JRRP,MSPC,NAC,NALP1,PP1044,SLEV1,VAMAS1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22861
MIM: 606636
HGNC: 14374
Ensembl: ENSG00000091592
Variants:
dbSNP: 22861
ClinVar: 22861
TCGA: ENSG00000091592
COSMIC: NLRP1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37278107 | 2024 | Low-level NLRP1 is associated with increased metastasis and risk of recurrence of non-melanoma skin cancer. | 0 |
| 37889986 | 2024 | Role of the NLRP1 inflammasome in skin cancer and inflammatory skin diseases. | 3 |
| 38411106 | 2024 | NLRP1 restricts porcine deltacoronavirus infection via IL-11 inhibiting the phosphorylation of the ERK signaling pathway. | 0 |
| 38540722 | 2024 | Increased NLRP1 mRNA and Protein Expression Suggests Inflammasome Activation in the Dorsolateral Prefrontal and Medial Orbitofrontal Cortex in Schizophrenia. | 0 |
| 37278107 | 2024 | Low-level NLRP1 is associated with increased metastasis and risk of recurrence of non-melanoma skin cancer. | 0 |
| 37889986 | 2024 | Role of the NLRP1 inflammasome in skin cancer and inflammatory skin diseases. | 3 |
| 38411106 | 2024 | NLRP1 restricts porcine deltacoronavirus infection via IL-11 inhibiting the phosphorylation of the ERK signaling pathway. | 0 |
| 38540722 | 2024 | Increased NLRP1 mRNA and Protein Expression Suggests Inflammasome Activation in the Dorsolateral Prefrontal and Medial Orbitofrontal Cortex in Schizophrenia. | 0 |
| 35776169 | 2023 | The role of NLRP1 and NLRP3 inflammasomes in the etiopathogeneses of pityriasis lichenoides chronica and mycosis fungoides: an immunohistochemical study. | 4 |
| 36207143 | 2023 | Immersion in Water Between 20-30(o)C Mediated Inflammations Marker to Reduced Pain Among Indonesian With Gout Arthritis: A Community-Based Randomized Controlled Trial. | 0 |
| 36416944 | 2023 | A common variant close to the "tripwire" linker region of NLRP1 contributes to severe COVID-19. | 3 |
| 36649710 | 2023 | The NLRP1 and CARD8 inflammasomes detect reductive stress. | 10 |
| 36649711 | 2023 | Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation. | 11 |
| 36736455 | 2023 | Skin Colonization with S. aureus Can Lead to Increased NLRP1 Inflammasome Activation in Patients with Atopic Dermatitis. | 3 |
| 36763875 | 2023 | Current understanding of the phenotypic spectrum of patients with NLRP1 variants. | 0 |
Citation
Dessen P
NLRP1 (NLR family pyrin domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43368/nlrp1-(nlr-family-pyrin-domain-containing-1)
