Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4881
MIM: 108960
HGNC: 7943
Ensembl: ENSG00000169418
Variants:
dbSNP: 4881
ClinVar: 4881
TCGA: ENSG00000169418
COSMIC: NPR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169418 | ENST00000368680 | P16066 |
| ENSG00000169418 | ENST00000368680 | A0A140VJE6 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37080586 | 2023 | Biallelic NPR1 loss of function variants are responsible for neonatal systemic hypertension. | 1 |
| 37356621 | 2023 | Dual deletion of guanylyl cyclase-A and p38 mitogen-activated protein kinase in podocytes with aldosterone administration causes glomerular intra-capillary thrombi. | 0 |
| 37080586 | 2023 | Biallelic NPR1 loss of function variants are responsible for neonatal systemic hypertension. | 1 |
| 37356621 | 2023 | Dual deletion of guanylyl cyclase-A and p38 mitogen-activated protein kinase in podocytes with aldosterone administration causes glomerular intra-capillary thrombi. | 0 |
| 34671022 | 2021 | Natriuretic peptide receptor a promotes gastric malignancy through angiogenesis process. | 4 |
| 34930837 | 2021 | Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators. | 9 |
| 34671022 | 2021 | Natriuretic peptide receptor a promotes gastric malignancy through angiogenesis process. | 4 |
| 34930837 | 2021 | Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators. | 9 |
| 33375031 | 2020 | ANP and BNP Exert Anti-Inflammatory Action via NPR-1/cGMP Axis by Interfering with Canonical, Non-Canonical, and Alternative Routes of Inflammasome Activation in Human THP1 Cells. | 11 |
| 33375031 | 2020 | ANP and BNP Exert Anti-Inflammatory Action via NPR-1/cGMP Axis by Interfering with Canonical, Non-Canonical, and Alternative Routes of Inflammasome Activation in Human THP1 Cells. | 11 |
| 30696704 | 2019 | The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate. | 9 |
| 31430210 | 2019 | Blood Pressure-Associated Genetic Variants in the Natriuretic Peptide Receptor 1 Gene Modulate Guanylate Cyclase Activity. | 9 |
| 30696704 | 2019 | The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate. | 9 |
| 31430210 | 2019 | Blood Pressure-Associated Genetic Variants in the Natriuretic Peptide Receptor 1 Gene Modulate Guanylate Cyclase Activity. | 9 |
| 29409758 | 2018 | Regulation of natriuretic peptides postprandially in vivo and of their receptors in adipocytes by fatty acids in vitro. | 2 |
Citation
Dessen P
NPR1 (natriuretic peptide receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43382/
