Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10298
MIM: 605451
HGNC: 16059
Ensembl: ENSG00000130669
Variants:
dbSNP: 10298
ClinVar: 10298
TCGA: ENSG00000130669
COSMIC: PAK4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36470541 | 2023 | Pan-cancer analysis identifies the immunological and prognostic role of PAK4. | 1 |
| 36593383 | 2023 | The role of p21-activated kinase 4 in the progression of oral squamous cell carcinoma by targeting PI3K-AKT signaling pathway. | 0 |
| 36470541 | 2023 | Pan-cancer analysis identifies the immunological and prognostic role of PAK4. | 1 |
| 36593383 | 2023 | The role of p21-activated kinase 4 in the progression of oral squamous cell carcinoma by targeting PI3K-AKT signaling pathway. | 0 |
| 33765367 | 2022 | miR-425 regulates ovarian cancer proliferation, metastasis, and apoptosis by repressing PAK4 expression. | 1 |
| 35798086 | 2022 | PAK4 in cancer development: Emerging player and therapeutic opportunities. | 2 |
| 35883575 | 2022 | Targeting of p21-Activated Kinase 4 Radiosensitizes Glioblastoma Cells via Impaired DNA Repair. | 1 |
| 35984204 | 2022 | PAK4 expression is associated with the prognosis in non-small cell lung cancer. | 0 |
| 33765367 | 2022 | miR-425 regulates ovarian cancer proliferation, metastasis, and apoptosis by repressing PAK4 expression. | 1 |
| 35798086 | 2022 | PAK4 in cancer development: Emerging player and therapeutic opportunities. | 2 |
| 35883575 | 2022 | Targeting of p21-Activated Kinase 4 Radiosensitizes Glioblastoma Cells via Impaired DNA Repair. | 1 |
| 35984204 | 2022 | PAK4 expression is associated with the prognosis in non-small cell lung cancer. | 0 |
| 33168646 | 2021 | Targeting PAK4 Inhibits Ras-Mediated Signaling and Multiple Oncogenic Pathways in High-Risk Rhabdomyosarcoma. | 15 |
| 33414491 | 2021 | p21-activated kinases as viable therapeutic targets for the treatment of high-risk Ewing sarcoma. | 6 |
| 33710605 | 2021 | Silencing of SETD6 inhibits the tumorigenesis of oral squamous cell carcinoma by inhibiting methylation of PAK4 and RelA. | 2 |
Citation
Dessen P
PAK4 (p21 (RAC1) activated kinase 4)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43393/pak4-(p21-(rac1)-activated-kinase-4)
