Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57144
MIM: 608038
HGNC: 15916
Ensembl: ENSG00000101349
Variants:
dbSNP: 57144
ClinVar: 57144
TCGA: ENSG00000101349
COSMIC: PAK5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101349 | ENST00000353224 | Q9P286 |
| ENSG00000101349 | ENST00000378423 | Q9P286 |
| ENSG00000101349 | ENST00000378429 | Q9P286 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37437827 | 2023 | PAK5 potentiates slug transactivation of N-cadherin to facilitate metastasis of renal cell carcinoma. | 0 |
| 37437827 | 2023 | PAK5 potentiates slug transactivation of N-cadherin to facilitate metastasis of renal cell carcinoma. | 0 |
| 35242138 | 2022 | The Predictive Value of PAK7 Mutation for Immune Checkpoint Inhibitors Therapy in Non-Small Cell Cancer. | 5 |
| 36905268 | 2022 | PAK5 is a potential target in myelodysplastic syndrome through interacting with LMO2 and GATA1. | 0 |
| 35242138 | 2022 | The Predictive Value of PAK7 Mutation for Immune Checkpoint Inhibitors Therapy in Non-Small Cell Cancer. | 5 |
| 36905268 | 2022 | PAK5 is a potential target in myelodysplastic syndrome through interacting with LMO2 and GATA1. | 0 |
| 33542180 | 2021 | P21-activated kinase 5 potentiates the chemoresistant phenotype of liver cancer. | 4 |
| 34143694 | 2021 | MiR-145-5p modulates lipid metabolism and M2 macrophage polarization by targeting PAK7 and regulating β-catenin signaling in hyperlipidemia. | 4 |
| 34165002 | 2021 | Inhibiting p21-activated kinase (PAK7) enhances radiosensitivity in hepatocellular carcinoma. | 5 |
| 34586742 | 2021 | PAK5-stabilized Smuc confers renal cell carcinoma metastasis. | 2 |
| 34936874 | 2021 | PAK5 promotes RNA helicase DDX5 sumoylation and miRNA-10b processing in a kinase-dependent manner in breast cancer. | 9 |
| 33542180 | 2021 | P21-activated kinase 5 potentiates the chemoresistant phenotype of liver cancer. | 4 |
| 34143694 | 2021 | MiR-145-5p modulates lipid metabolism and M2 macrophage polarization by targeting PAK7 and regulating β-catenin signaling in hyperlipidemia. | 4 |
| 34165002 | 2021 | Inhibiting p21-activated kinase (PAK7) enhances radiosensitivity in hepatocellular carcinoma. | 5 |
| 34586742 | 2021 | PAK5-stabilized Smuc confers renal cell carcinoma metastasis. | 2 |
Citation
Dessen P
PAK5 (p21 (RAC1) activated kinase 5)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43394/pak5-(p21-(rac1)-activated-kinase-5)
