FEV (FEV transcription factor, ETS family member)

2003-02-01 Affiliation

Identity

HGNC

FEV

LOCATION

2q35

LOCUSID

54738

ALIAS

HSRNAFEV,PET-1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 54738
MIM: 607150
HGNC: 18562
Ensembl: ENSG00000163497

Variants:

dbSNP: 54738
ClinVar: 54738
TCGA: ENSG00000163497
COSMIC: FEV

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000163497	ENST00000295727	Q99581

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Transcriptional misregulation in cancer	KEGG	ko05202
Transcriptional misregulation in cancer	KEGG	hsa05202

References

Pubmed ID	Year	Title	Citations
19874574	2009	Genetical genomic determinants of alcohol consumption in rats and humans.	93
15758173	2005	A differentially autoregulated Pet-1 enhancer region is a critical target of the transcriptional cascade that governs serotonin neuron development.	31
20468064	2010	Association study of 182 candidate genes in anorexia nervosa.	30
20546612	2010	The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.	19
23591790	2013	Fev regulates hematopoietic stem cell development via ERK signaling.	17
17597646	2007	Sudden infant death syndrome: rare mutation in the serotonin system FEV gene.	13
24100022	2013	Convergent effects of mouse Pet-1 deletion and human PET-1 variation on amygdala fear and threat processing.	12
15003288	2004	The Ets transcription factor Fev is specifically expressed in the human central serotonergic neurons.	11
12761502	2003	FEV acts as a transcriptional repressor through its DNA-binding ETS domain and alanine-rich domain.	8
20048018	2010	The ETS oncogene family transcription factor FEV identifies serotonin-producing cells in normal and neoplastic small intestine.	8

Citation

Dessen P

FEV (FEV transcription factor, ETS family member)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/434/fev-(fev-transcription-factor-ets-family-member)