Identity
HGNC
LOCATION
9p24.1
LOCUSID
ALIAS
B7DC,Btdc,CD273,PD-L2,PDCD1L2,PDL2,bA574F11.2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80380
MIM: 605723
HGNC: 18731
Ensembl: ENSG00000197646
Variants:
dbSNP: 80380
ClinVar: 80380
TCGA: ENSG00000197646
COSMIC: PDCD1LG2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000197646 | ENST00000397747 | Q9BQ51 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38956724 | 2024 | Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity. | 0 |
| 38956724 | 2024 | Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity. | 0 |
| 35466759 | 2023 | The Overexpression of Programmed Death-Ligand 2 in Uterine Adenosarcoma: Correlation with High-Grade Morphology, Mutant Type TP53 Expression and Clinical Outcomes. | 2 |
| 36281760 | 2023 | Programmed cell death 1 and programmed cell death ligand 1 expression in invasive breast carcinoma using CAL10 and NAT105 immunostaining. | 0 |
| 36522474 | 2023 | Evolving landscape of PD-L2: bring new light to checkpoint immunotherapy. | 24 |
| 36656207 | 2023 | PD-L1 and PD-L2 expression in colorectal cancer. | 1 |
| 36830609 | 2023 | Expression of IDO1 and PD-L2 in Patients with Benign Lymphadenopathies and Association with Autoimmune Diseases. | 0 |
| 37006239 | 2023 | Pan-cancer analysis identifies PD-L2 as a tumor promotor in the tumor microenvironment. | 4 |
| 37060883 | 2023 | The expression of programmed death-ligand 1 and programmed death-ligand 2 in endometrial carcinosarcoma: Correlation with mismatch repair protein expression status, tumor-infiltrating lymphocyte infiltration, and clinical outcomes. | 1 |
| 37146414 | 2023 | PD-L1 and PD-L2 immune checkpoint protein induction by type III interferon in non-small cell lung cancer cells. | 3 |
| 37402054 | 2023 | PD-L2 overexpression on tumor-associated macrophages is one of the predictors for better prognosis in lung adenocarcinoma. | 1 |
| 37768345 | 2023 | An alternatively spliced PD-L1 isoform PD-L1∆3, and PD-L2 expression in breast cancers: implications for eligibility scoring and immunotherapy response. | 1 |
| 37828429 | 2023 | Cholinergic signaling influences the expression of immune checkpoint inhibitors, PD-L1 and PD-L2, and tumor hallmarks in human colorectal cancer tissues and cell lines. | 3 |
| 35466759 | 2023 | The Overexpression of Programmed Death-Ligand 2 in Uterine Adenosarcoma: Correlation with High-Grade Morphology, Mutant Type TP53 Expression and Clinical Outcomes. | 2 |
| 36281760 | 2023 | Programmed cell death 1 and programmed cell death ligand 1 expression in invasive breast carcinoma using CAL10 and NAT105 immunostaining. | 0 |
Citation
Dessen P
PDCD1LG2 (programmed cell death 1 ligand 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43401
