Identity
HGNC
LOCATION
5q14.1
LOCUSID
ALIAS
GRF2,RAS-GRF2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5924
MIM: 606614
HGNC: 9876
Ensembl: ENSG00000113319
Variants:
dbSNP: 5924
ClinVar: 5924
TCGA: ENSG00000113319
COSMIC: RASGRF2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000113319 | ENST00000265080 | O14827 |
| ENSG00000113319 | ENST00000265080 | A0A2X0SFL3 |
| ENSG00000113319 | ENST00000503795 | D6RAS9 |
| ENSG00000113319 | ENST00000638442 | A0A1W2PP99 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37029817 | 2023 | Genetic variants of SOS2, MAP2K1 and RASGRF2 in the RAS pathway genes predict survival of HBV-related hepatocellular carcinoma patients. | 4 |
| 37029817 | 2023 | Genetic variants of SOS2, MAP2K1 and RASGRF2 in the RAS pathway genes predict survival of HBV-related hepatocellular carcinoma patients. | 4 |
| 32298357 | 2020 | Reciprocal expression of Annexin A6 and RasGRF2 discriminates rapidly growing from invasive triple negative breast cancer subsets. | 0 |
| 32298357 | 2020 | Reciprocal expression of Annexin A6 and RasGRF2 discriminates rapidly growing from invasive triple negative breast cancer subsets. | 0 |
| 30359168 | 2019 | RasGRF2 promotes migration and invasion of colorectal cancer cells by modulating expression of MMP9 through Src/Akt/NF-κB pathway. | 12 |
| 30359168 | 2019 | RasGRF2 promotes migration and invasion of colorectal cancer cells by modulating expression of MMP9 through Src/Akt/NF-κB pathway. | 12 |
| 30249655 | 2018 | Human Endogenous Retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line model. | 13 |
| 30249655 | 2018 | Human Endogenous Retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line model. | 13 |
| 27856453 | 2017 | RasGRF Couples Nox4-Dependent Endoplasmic Reticulum Signaling to Ras. | 9 |
| 27856453 | 2017 | RasGRF Couples Nox4-Dependent Endoplasmic Reticulum Signaling to Ras. | 9 |
| 27992614 | 2016 | A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men. | 0 |
| 27992614 | 2016 | A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men. | 0 |
| 24692549 | 2014 | βArrestin1 regulates the guanine nucleotide exchange factor RasGRF2 expression and the small GTPase Rac-mediated formation of membrane protrusion and cell motility. | 15 |
| 24692549 | 2014 | βArrestin1 regulates the guanine nucleotide exchange factor RasGRF2 expression and the small GTPase Rac-mediated formation of membrane protrusion and cell motility. | 15 |
| 23827383 | 2013 | A genome-wide association study for malignant mesothelioma risk. | 18 |
Citation
Dessen P
RASGRF2 (Ras protein specific guanine nucleotide releasing factor 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43454/rasgrf2-(ras-protein-specific-guanine-nucleotide-releasing-factor-2)
