Identity
HGNC
LOCATION
11q24.3
LOCUSID
ALIAS
GC-GAP,GRIT,PX-RICS,RICS,p200RhoGAP,p250GAP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9743
MIM: 608541
HGNC: 17399
Ensembl: ENSG00000134909
Variants:
dbSNP: 9743
ClinVar: 9743
TCGA: ENSG00000134909
COSMIC: ARHGAP32
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37343594 | 2023 | Association between Grit and depressive symptoms at the timing of job start among medical residents during the COVID-19 pandemic in Japan: a cross-sectional study. | 1 |
| 37343594 | 2023 | Association between Grit and depressive symptoms at the timing of job start among medical residents during the COVID-19 pandemic in Japan: a cross-sectional study. | 1 |
| 35662113 | 2022 | Circ_ARHGAP32 acts as miR-665 sponge to upregulate FGF2 to promote ox-LDL induced vascular smooth muscle cells proliferation and migration. | 3 |
| 35662113 | 2022 | Circ_ARHGAP32 acts as miR-665 sponge to upregulate FGF2 to promote ox-LDL induced vascular smooth muscle cells proliferation and migration. | 3 |
| 22530067 | 2012 | The p250GAP gene is associated with risk for schizophrenia and schizotypal personality traits. | 11 |
| 23226367 | 2012 | p250GAP is a novel player in the Cdh1-APC/Smurf1 pathway of axon growth regulation. | 15 |
| 22530067 | 2012 | The p250GAP gene is associated with risk for schizophrenia and schizotypal personality traits. | 11 |
| 23226367 | 2012 | p250GAP is a novel player in the Cdh1-APC/Smurf1 pathway of axon growth regulation. | 15 |
| 20308060 | 2010 | The PX-RICS-14-3-3zeta/theta complex couples N-cadherin-beta-catenin with dynein-dynactin to mediate its export from the endoplasmic reticulum. | 12 |
| 20308060 | 2010 | The PX-RICS-14-3-3zeta/theta complex couples N-cadherin-beta-catenin with dynein-dynactin to mediate its export from the endoplasmic reticulum. | 12 |
| 18451111 | 2008 | PX-RICS mediates ER-to-Golgi transport of the N-cadherin/beta-catenin complex. | 19 |
| 18577589 | 2008 | An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. | 291 |
| 18451111 | 2008 | PX-RICS mediates ER-to-Golgi transport of the N-cadherin/beta-catenin complex. | 19 |
| 18577589 | 2008 | An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. | 291 |
| 17663722 | 2007 | PX-RICS, a novel splicing variant of RICS, is a main isoform expressed during neural development. | 12 |
Citation
Dessen P
ARHGAP32 (Rho GTPase activating protein 32)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43468
