DSTYK (dual serine/threonine and tyrosine protein kinase)

2006-10-01  

Identity

HGNC
DSTYK
LOCATION
1q32.1
LOCUSID
25778
ALIAS
CAKUT1,DustyPK,HDCMD38P,RIP5,RIPK5,SPG23
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 25778
MIM: 612666
HGNC: 29043
Ensembl: ENSG00000133059

Variants:

dbSNP: 25778
ClinVar: 25778
TCGA: ENSG00000133059
COSMIC: DSTYK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133059ENST00000367161Q6XUX3
ENSG00000133059ENST00000367162Q6XUX3
ENSG00000133059ENST00000615388Q6XUX3

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
238629742013Mutations in DSTYK and dominant urinary tract malformations.41
281575402017Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23.6
171236482006Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain.4
292380452017RIPK3 promotes adenovirus type 5 activity.3

Citation

Dessen P

DSTYK (dual serine/threonine and tyrosine protein kinase)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43472/dstyk-(dual-serine-threonine-and-tyrosine-protein-kinase)