Identity
HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
CAKUT1,DustyPK,HDCMD38P,RIP5,RIPK5,SPG23
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25778
MIM: 612666
HGNC: 29043
Ensembl: ENSG00000133059
Variants:
dbSNP: 25778
ClinVar: 25778
TCGA: ENSG00000133059
COSMIC: DSTYK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000133059 | ENST00000367161 | Q6XUX3 |
| ENSG00000133059 | ENST00000367162 | Q6XUX3 |
| ENSG00000133059 | ENST00000615388 | Q6XUX3 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37746849 | 2023 | Mouse and human studies support DSTYK loss of function as a low-penetrance and variable expressivity risk factor for congenital urinary tract anomalies. | 0 |
| 37746849 | 2023 | Mouse and human studies support DSTYK loss of function as a low-penetrance and variable expressivity risk factor for congenital urinary tract anomalies. | 0 |
| 36169652 | 2022 | DSTYK inhibition increases the sensitivity of lung cancer cells to T cell-mediated cytotoxicity. | 3 |
| 36555181 | 2022 | Aberrations in FGFR1, FGFR2, and RIP5 Expression in Human Congenital Anomalies of the Kidney and Urinary Tract (CAKUT). | 5 |
| 36169652 | 2022 | DSTYK inhibition increases the sensitivity of lung cancer cells to T cell-mediated cytotoxicity. | 3 |
| 36555181 | 2022 | Aberrations in FGFR1, FGFR2, and RIP5 Expression in Human Congenital Anomalies of the Kidney and Urinary Tract (CAKUT). | 5 |
| 35011659 | 2021 | DSTYK Enhances Chemoresistance in Triple-Negative Breast Cancer Cells. | 3 |
| 35011659 | 2021 | DSTYK Enhances Chemoresistance in Triple-Negative Breast Cancer Cells. | 3 |
| 28157540 | 2017 | Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23. | 16 |
| 29238045 | 2017 | RIPK3 promotes adenovirus type 5 activity. | 11 |
| 28157540 | 2017 | Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23. | 16 |
| 29238045 | 2017 | RIPK3 promotes adenovirus type 5 activity. | 11 |
| 23862974 | 2013 | Mutations in DSTYK and dominant urinary tract malformations. | 61 |
| 23862974 | 2013 | Mutations in DSTYK and dominant urinary tract malformations. | 61 |
| 17123648 | 2006 | Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain. | 11 |
Citation
Dessen P
DSTYK (dual serine/threonine and tyrosine protein kinase)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43472/dstyk-(dual-serine-threonine-and-tyrosine-protein-kinase)
