SNX27 (sorting nexin 27)

2006-10-01  

Identity

HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
MRT1,MY014
FUSION GENES

Other Information

Locus ID:

NCBI: 81609
MIM: 611541
HGNC: 20073
Ensembl: ENSG00000143376

Variants:

dbSNP: 81609
ClinVar: 81609
TCGA: ENSG00000143376
COSMIC: SNX27

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143376ENST00000368841H7C603
ENSG00000143376ENST00000368843Q96L92
ENSG00000143376ENST00000458013Q96L92
ENSG00000143376ENST00000482791A0A2R8Y3S6
ENSG00000143376ENST00000642349A0A2R8YD75
ENSG00000143376ENST00000642376A0A2R8Y8A7
ENSG00000143376ENST00000642479A0A2R8Y871

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

References

Pubmed IDYearTitleCitations
348660352022Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus.7
350222172022SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.23
360292092022Circ_SNX27 regulates hepatocellular carcinoma development via miR-637/FGFR1 axis.2
363262722022HPV-18E6 Inhibits Interactions between TANC2 and SNX27 in a PBM-Dependent Manner and Promotes Increased Cell Proliferation.2
348660352022Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus.7
350222172022SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.23
360292092022Circ_SNX27 regulates hepatocellular carcinoma development via miR-637/FGFR1 axis.2
363262722022HPV-18E6 Inhibits Interactions between TANC2 and SNX27 in a PBM-Dependent Manner and Promotes Increased Cell Proliferation.2
336059792021Phosphorylation of SNX27 by MAPK11/14 links cellular stress-signaling pathways with endocytic recycling.20
350959132021Sorting Nexin 27 Enables MTOC and Secretory Machinery Translocation to the Immune Synapse.2
336059792021Phosphorylation of SNX27 by MAPK11/14 links cellular stress-signaling pathways with endocytic recycling.20
350959132021Sorting Nexin 27 Enables MTOC and Secretory Machinery Translocation to the Immune Synapse.2
317211752020Sorting nexin 27 (SNX27) variants associated with seizures, developmental delay, behavioral disturbance, and subcortical brain abnormalities.6
318207822020SNX27-retromer assembly recycles MT1-MMP to invadopodia and promotes breast cancer metastasis.23
321160232020SNX27 regulates DRA activity and mediates its direct recycling by PDZ-interaction in early endosomes at the apical pole of Caco2 cells.4

Citation

Dessen P

SNX27 (sorting nexin 27)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43499/snx27-(sorting-nexin-27)