Identity
HGNC
LOCATION
12q14.2
LOCUSID
ALIAS
ARHGAP13,NMTC2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57522
MIM: 606523
HGNC: 17382
Ensembl: ENSG00000196935
Variants:
dbSNP: 57522
ClinVar: 57522
TCGA: ENSG00000196935
COSMIC: SRGAP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000196935 | ENST00000355086 | Q7Z6B7 |
| ENSG00000196935 | ENST00000543397 | G5EA48 |
| ENSG00000196935 | ENST00000631006 | G5EA48 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33984363 | 2021 | Identification of SRGAP2 as a potential oncogene and a prognostic biomarker in hepatocellular carcinoma. | 4 |
| 33984363 | 2021 | Identification of SRGAP2 as a potential oncogene and a prognostic biomarker in hepatocellular carcinoma. | 4 |
| 29160905 | 2018 | Regulated recruitment of SRGAP1 modulates RhoA signaling for contractility during epithelial junction maturation. | 5 |
| 29234151 | 2018 | SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis. | 21 |
| 29160905 | 2018 | Regulated recruitment of SRGAP1 modulates RhoA signaling for contractility during epithelial junction maturation. | 5 |
| 29234151 | 2018 | SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis. | 21 |
| 27923383 | 2016 | srGAP1 mediates the migration inhibition effect of Slit2-Robo1 in colorectal cancer. | 19 |
| 27923383 | 2016 | srGAP1 mediates the migration inhibition effect of Slit2-Robo1 in colorectal cancer. | 19 |
| 26026080 | 2015 | MicroRNA-145 Promotes the Phenotype of Human Glioblastoma Cells Selected for Invasion. | 13 |
| 26026792 | 2015 | Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract. | 35 |
| 26026080 | 2015 | MicroRNA-145 Promotes the Phenotype of Human Glioblastoma Cells Selected for Invasion. | 13 |
| 26026792 | 2015 | Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract. | 35 |
| 25134534 | 2014 | Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women. | 40 |
| 25150978 | 2014 | An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration. | 47 |
| 25134534 | 2014 | Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women. | 40 |
Citation
Dessen P
SRGAP1 (SLIT-ROBO Rho GTPase activating protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43502/srgap1-(slit-robo-rho-gtpase-activating-protein-1)
