STK24 (serine/threonine kinase 24)

2006-10-01  

Identity

HGNC
LOCATION
13q32.2
LOCUSID
ALIAS
HEL-S-95,MST3,MST3B,STE20,STK3
FUSION GENES

Other Information

Locus ID:

NCBI: 8428
MIM: 604984
HGNC: 11403
Ensembl: ENSG00000102572

Variants:

dbSNP: 8428
ClinVar: 8428
TCGA: ENSG00000102572
COSMIC: STK24

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102572ENST00000376547Q9Y6E0
ENSG00000102572ENST00000376554Q5JV98
ENSG00000102572ENST00000397517B4DR80
ENSG00000102572ENST00000418038Q5JV99
ENSG00000102572ENST00000444574H0Y630
ENSG00000102572ENST00000539966Q9Y6E0
ENSG00000102572ENST00000539966Q5U0E6

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Programmed Cell DeathREACTOMER-HSA-5357801
ApoptosisREACTOMER-HSA-109581
Apoptotic execution phaseREACTOMER-HSA-75153
Apoptotic cleavage of cellular proteinsREACTOMER-HSA-111465

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382291832024Protein Kinase STK24 Promotes Tumor Immune Evasion via the AKT-PD-L1 Axis.1
382291832024Protein Kinase STK24 Promotes Tumor Immune Evasion via the AKT-PD-L1 Axis.1
367203102023Serine/threonine-protein kinase STK24 induces tumorigenesis by regulating the STAT3/VEGFA signaling pathway.1
374900002023STE20-type kinases MST3 and MST4 promote the progression of hepatocellular carcinoma: Evidence from human cell culture and expression profiling of liver biopsies.1
367203102023Serine/threonine-protein kinase STK24 induces tumorigenesis by regulating the STAT3/VEGFA signaling pathway.1
374900002023STE20-type kinases MST3 and MST4 promote the progression of hepatocellular carcinoma: Evidence from human cell culture and expression profiling of liver biopsies.1
324363592020STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons.8
324363592020STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons.8
310341652019microRNA-222 promotes colorectal cancer cell migration and invasion by targeting MST3.11
311735062019Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in humans.17
310341652019microRNA-222 promotes colorectal cancer cell migration and invasion by targeting MST3.11
311735062019Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in humans.17
295571822018STK24 expression is modulated by DNA copy number/methylation in lung adenocarcinoma and predicts poor survival.10
295571822018STK24 expression is modulated by DNA copy number/methylation in lung adenocarcinoma and predicts poor survival.10
269108432016MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer.25

Citation

Dessen P

STK24 (serine/threonine kinase 24)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43509/stk24-(serine-threonine-kinase-24)