STK33 (serine/threonine kinase 33)

2006-10-01  

Identity

HGNC
STK33
LOCATION
11p15.4
LOCUSID
65975
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 65975
MIM: 607670
HGNC: 14568
Ensembl: ENSG00000130413

Variants:

dbSNP: 65975
ClinVar: 65975
TCGA: ENSG00000130413
COSMIC: STK33

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130413ENST00000315204Q9BYT3
ENSG00000130413ENST00000358872F8WAK5
ENSG00000130413ENST00000396672Q9BYT3
ENSG00000130413ENST00000418597C9J319
ENSG00000130413ENST00000422559C9J6X7
ENSG00000130413ENST00000431279C9J8B1
ENSG00000130413ENST00000444064A0A0C4DH60
ENSG00000130413ENST00000447869Q9BYT3
ENSG00000130413ENST00000454443C9J5G1
ENSG00000130413ENST00000457885C9JCS6
ENSG00000130413ENST00000524760H0YEZ7
ENSG00000130413ENST00000526360E9PNP9
ENSG00000130413ENST00000534493B4DDH2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
371010092023Interaction between STK33 and autophagy promoted renal cell carcinoma metastasis by regulating mTOR/ULK1 signaling pathway.0
371010092023Interaction between STK33 and autophagy promoted renal cell carcinoma metastasis by regulating mTOR/ULK1 signaling pathway.0
341555122021Novel frameshift mutation in STK33 is associated with asthenozoospermia and multiple morphological abnormalities of the flagella.12
341555122021Novel frameshift mutation in STK33 is associated with asthenozoospermia and multiple morphological abnormalities of the flagella.12
307606312019STK33/ERK2 signal pathway contribute the tumorigenesis of colorectal cancer HCT15 cells.3
307606312019STK33/ERK2 signal pathway contribute the tumorigenesis of colorectal cancer HCT15 cells.3
293674282018Krüppel-like Factor 4 Suppresses Serine/Threonine Kinase 33 Activation and Metastasis of Gastric Cancer through Reversing Epithelial-Mesenchymal Transition.20
293674282018Krüppel-like Factor 4 Suppresses Serine/Threonine Kinase 33 Activation and Metastasis of Gastric Cancer through Reversing Epithelial-Mesenchymal Transition.20
288954112017Knockdown of human serine/threonine kinase 33 suppresses human small cell lung carcinoma by blocking RPS6/BAD signaling transduction.4
290383482017STK33 Promotes Growth and Progression of Pancreatic Cancer as a Critical Downstream Mediator of HIF1α.22
288954112017Knockdown of human serine/threonine kinase 33 suppresses human small cell lung carcinoma by blocking RPS6/BAD signaling transduction.4
290383482017STK33 Promotes Growth and Progression of Pancreatic Cancer as a Critical Downstream Mediator of HIF1α.22
253987722016STK33 promotes hepatocellular carcinoma through binding to c-Myc.14
274141932016STK33 potentiates the malignancy of hypopharyngeal squamous carcinoma: Possible relation to calcium.4
253987722016STK33 promotes hepatocellular carcinoma through binding to c-Myc.14

Citation

Dessen P

STK33 (serine/threonine kinase 33)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43513/stk33-(serine-threonine-kinase-33)