STK38 (serine/threonine kinase 38)

2006-10-01  

Identity

HGNC
LOCATION
6p21.31
LOCUSID
ALIAS
NDR,NDR1
FUSION GENES

Other Information

Locus ID:

NCBI: 11329
MIM: 606964
HGNC: 17847
Ensembl: ENSG00000112079

Variants:

dbSNP: 11329
ClinVar: 11329
TCGA: ENSG00000112079
COSMIC: STK38

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112079ENST00000229812Q15208
ENSG00000112079ENST00000229812A0A024RD18

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379874472023Microautophagy regulated by STK38 and GABARAPs is essential to repair lysosomes and prevent aging.3
379874472023Microautophagy regulated by STK38 and GABARAPs is essential to repair lysosomes and prevent aging.3
355089872022NDR1 increases NOTCH1 signaling activity by impairing Fbw7 mediated NICD degradation to enhance breast cancer stem cell properties.6
362328932022Prognostic and Immunological Role of STK38 across Cancers: Friend or Foe?3
355089872022NDR1 increases NOTCH1 signaling activity by impairing Fbw7 mediated NICD degradation to enhance breast cancer stem cell properties.6
362328932022Prognostic and Immunological Role of STK38 across Cancers: Friend or Foe?3
331456122021The STK38-XPO1 axis, a new actor in physiology and cancer.6
346704782021STK38 is a PPARγ-interacting protein promoting adipogenesis.1
331456122021The STK38-XPO1 axis, a new actor in physiology and cancer.6
346704782021STK38 is a PPARγ-interacting protein promoting adipogenesis.1
315443102019STK38 kinase acts as XPO1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoes.25
315443102019STK38 kinase acts as XPO1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoes.25
295491642018Kir2.1 Interaction with Stk38 Promotes Invasion and Metastasis of Human Gastric Cancer by Enhancing MEKK2-MEK1/2-ERK1/2 Signaling.29
299833732018Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment.12
300183362018Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop.14

Citation

Dessen P

STK38 (serine/threonine kinase 38)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43516/stk38-(serine-threonine-kinase-38)