C12orf75 (chromosome 12 open reading frame 75)

2007-01-01  

Identity

HGNC
C12orf75
LOCATION
12q23.3
LOCUSID
387882
ALIAS
AGD3,OCC-1,OCC1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 387882
HGNC: 35164
Ensembl: ENSG00000235162

Variants:

dbSNP: 387882
ClinVar: 387882
TCGA: ENSG00000235162
COSMIC: C12orf75

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000235162ENST00000443585Q8TAD7
ENSG00000235162ENST00000549893F8VXK5
ENSG00000235162ENST00000549934F8VQD4
ENSG00000235162ENST00000552457F8W1S6
ENSG00000235162ENST00000612117I7HHH9

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
353977132022OCC-1D regulates Wnt signaling pathway: potential role of long noncoding RNA in colorectal cancer.0
355766832022Downregulation of C12orf75 gene inhibits migration and invasion of liver cancer cell via suppressing the Wnt/β-catenin signaling pathway in vitro.1
353977132022OCC-1D regulates Wnt signaling pathway: potential role of long noncoding RNA in colorectal cancer.0
355766832022Downregulation of C12orf75 gene inhibits migration and invasion of liver cancer cell via suppressing the Wnt/β-catenin signaling pathway in vitro.1
340747992021Pan-cancer analysis of the prognostic value of C12orf75 based on data mining.0
340747992021Pan-cancer analysis of the prognostic value of C12orf75 based on data mining.0
302183502018Overexpressed in colorectal carcinoma gene (OCC-1) upregulation and APPL2 gene downregulation in breast cancer specimens.2
302183502018Overexpressed in colorectal carcinoma gene (OCC-1) upregulation and APPL2 gene downregulation in breast cancer specimens.2
279868942017Alternative splicing of the OCC-1 gene generates three splice variants and a novel exonic microRNA, which regulate the Wnt signaling pathway.9
279868942017Alternative splicing of the OCC-1 gene generates three splice variants and a novel exonic microRNA, which regulate the Wnt signaling pathway.9

Citation

Dessen P

C12orf75 (chromosome 12 open reading frame 75)

Atlas Genet Cytogenet Oncol Haematol. 2007-01-01

Online version: http://atlasgeneticsoncology.org/gene/43578/c12orf75-(chromosome-12-open-reading-frame-75)