Identity
HGNC
LOCATION
5q15
LOCUSID
ALIAS
CAP,IRAP,P-LAP,PLAP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4012
MIM: 151300
HGNC: 6656
Ensembl: ENSG00000113441
Variants:
dbSNP: 4012
ClinVar: 4012
TCGA: ENSG00000113441
COSMIC: LNPEP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000113441 | ENST00000231368 | Q9UIQ6 |
| ENSG00000113441 | ENST00000395770 | Q9UIQ6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36716917 | 2023 | Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis. | 4 |
| 36716917 | 2023 | Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis. | 4 |
| 32619880 | 2020 | The role of LNPEP and ANPEP gene polymorphisms in the pathogenesis of pre-eclampsia. | 0 |
| 32619880 | 2020 | The role of LNPEP and ANPEP gene polymorphisms in the pathogenesis of pre-eclampsia. | 0 |
| 30581499 | 2018 | Differential Gene Expression Profile of Renin-Angiotensin System in the Left Atrium in Mitral Regurgitation Patients. | 4 |
| 30581499 | 2018 | Differential Gene Expression Profile of Renin-Angiotensin System in the Left Atrium in Mitral Regurgitation Patients. | 4 |
| 28035472 | 2017 | Insulin-regulated aminopeptidase immunoreactivity is abundantly present in human hypothalamus and posterior pituitary gland, with reduced expression in paraventricular and suprachiasmatic neurons in chronic schizophrenia. | 3 |
| 28328206 | 2017 | Ligand-Induced Conformational Change of Insulin-Regulated Aminopeptidase: Insights on Catalytic Mechanism and Active Site Plasticity. | 24 |
| 28035472 | 2017 | Insulin-regulated aminopeptidase immunoreactivity is abundantly present in human hypothalamus and posterior pituitary gland, with reduced expression in paraventricular and suprachiasmatic neurons in chronic schizophrenia. | 3 |
| 28328206 | 2017 | Ligand-Induced Conformational Change of Insulin-Regulated Aminopeptidase: Insights on Catalytic Mechanism and Active Site Plasticity. | 24 |
| 26366890 | 2016 | Vasopressinase Activity: A Potential Early Biomarker for Detecting Cardiopulmonary Bypass-Associated Acute Kidney Injury? | 3 |
| 27501164 | 2016 | Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures. | 12 |
| 27834335 | 2016 | A PCR-RFLP method for detection of the LNPEP encoding human insulin-regulated aminopeptidase (IRAP) rs4869317 polymorphism. | 3 |
| 26366890 | 2016 | Vasopressinase Activity: A Potential Early Biomarker for Detecting Cardiopulmonary Bypass-Associated Acute Kidney Injury? | 3 |
| 27501164 | 2016 | Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures. | 12 |
Citation
Dessen P
LNPEP (leucyl and cystinyl aminopeptidase)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43606/lnpep-(leucyl-and-cystinyl-aminopeptidase)
