EGFL8 (EGF like domain multiple 8)

2011-10-01  

Identity

HGNC
EGFL8
LOCATION
6p21.32
LOCUSID
80864
ALIAS
C6orf8,NG3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80864
MIM: 609897
HGNC: 13944
Ensembl: ENSG00000241404

Variants:

dbSNP: 80864
ClinVar: 80864
TCGA: ENSG00000241404
COSMIC: EGFL8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000241404ENST00000333845Q99944
ENSG00000241404ENST00000333845A0A1U9X7N9
ENSG00000241404ENST00000395512Q99944
ENSG00000241404ENST00000395512A0A1U9X7N9
ENSG00000241404ENST00000432129Q5JP22

Expression (GTEx)

0
100
200
300
400
500
600
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.51
191438142009Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1.17
219657492011Down-regulation of EGFL8: a novel biomarker for advanced gastric cancer.2
205876102010Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.1
217376482011Down-regulation of EGFL8: a novel prognostic biomarker for patients with colorectal cancer.0

Citation

Dessen P

EGFL8 (EGF like domain multiple 8)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/43611/egfl8-(egf-like-domain-multiple-8)