Identity
HGNC
LOCATION
1p13.2
LOCUSID
ALIAS
MAGI-3,dJ730K3.2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 260425
MIM: 615943
HGNC: 29647
Ensembl: ENSG00000081026
Variants:
dbSNP: 260425
ClinVar: 260425
TCGA: ENSG00000081026
COSMIC: MAGI3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000081026 | ENST00000307546 | Q5TCQ9 |
| ENSG00000081026 | ENST00000369611 | Q5TCQ9 |
| ENSG00000081026 | ENST00000369615 | Q5TCQ9 |
| ENSG00000081026 | ENST00000369617 | Q5TCQ9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Rap1 signaling pathway | KEGG | hsa04015 |
| Rap1 signaling pathway | KEGG | ko04015 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34510826 | 2021 | Reduced MAGI3 level by HPV18E6 contributes to Wnt/β-catenin signaling activation and cervical cancer progression. | 4 |
| 34510826 | 2021 | Reduced MAGI3 level by HPV18E6 contributes to Wnt/β-catenin signaling activation and cervical cancer progression. | 4 |
| 32080912 | 2020 | Integrated analyses identify miR-34c-3p/MAGI3 axis for the Warburg metabolism in hepatocellular carcinoma. | 8 |
| 32080912 | 2020 | Integrated analyses identify miR-34c-3p/MAGI3 axis for the Warburg metabolism in hepatocellular carcinoma. | 8 |
| 29362392 | 2018 | Premature polyadenylation of MAGI3 is associated with diminished N(6)-methyladenosine in its large internal exon. | 15 |
| 29362392 | 2018 | Premature polyadenylation of MAGI3 is associated with diminished N(6)-methyladenosine in its large internal exon. | 15 |
| 28545409 | 2017 | Genetic variation and expression levels of tight junction genes identifies association between MAGI3 and inflammatory bowel disease. | 13 |
| 28545409 | 2017 | Genetic variation and expression levels of tight junction genes identifies association between MAGI3 and inflammatory bowel disease. | 13 |
| 27205883 | 2016 | Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer. | 15 |
| 27205883 | 2016 | Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer. | 15 |
| 26248734 | 2015 | MAGI3 Suppresses Glioma Cell Proliferation via Upregulation of PTEN Expression. | 13 |
| 26452219 | 2015 | MAGI3 negatively regulates Wnt/β-catenin signaling and suppresses malignant phenotypes of glioma cells. | 24 |
| 26248734 | 2015 | MAGI3 Suppresses Glioma Cell Proliferation via Upregulation of PTEN Expression. | 13 |
| 26452219 | 2015 | MAGI3 negatively regulates Wnt/β-catenin signaling and suppresses malignant phenotypes of glioma cells. | 24 |
| 21134377 | 2011 | MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells. | 35 |
Citation
Dessen P
MAGI3 (membrane associated guanylate kinase, WW and PDZ domain containing 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43638/magi3-(membrane-associated-guanylate-kinase-ww-and-pdz-domain-containing-3)
