Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 90249
MIM: 607869
HGNC: 12567
Ensembl: ENSG00000113763
Variants:
dbSNP: 90249
ClinVar: 90249
TCGA: ENSG00000113763
COSMIC: UNC5A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000113763 | ENST00000329542 | Q6ZN44 |
| ENSG00000113763 | ENST00000509580 | H0Y8R2 |
| ENSG00000113763 | ENST00000513890 | H0Y9G2 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29277614 | 2018 | Hepatocellular carcinoma-associated depletion of the netrin-1 receptor Uncoordinated Phenotype-5A (UNC5A) skews the hepatic unfolded protein response towards prosurvival outcomes. | 3 |
| 29720215 | 2018 | Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis. | 11 |
| 29277614 | 2018 | Hepatocellular carcinoma-associated depletion of the netrin-1 receptor Uncoordinated Phenotype-5A (UNC5A) skews the hepatic unfolded protein response towards prosurvival outcomes. | 3 |
| 29720215 | 2018 | Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis. | 11 |
| 28710382 | 2017 | Netrin-1 promotes glioma growth by activating NF-κB via UNC5A. | 11 |
| 28783179 | 2017 | Reciprocal antagonism between the netrin-1 receptor uncoordinated-phenotype-5A (UNC5A) and the hepatitis C virus. | 5 |
| 28710382 | 2017 | Netrin-1 promotes glioma growth by activating NF-κB via UNC5A. | 11 |
| 28783179 | 2017 | Reciprocal antagonism between the netrin-1 receptor uncoordinated-phenotype-5A (UNC5A) and the hepatitis C virus. | 5 |
| 24676280 | 2014 | The Fanconi anemia group C protein interacts with uncoordinated 5A and delays apoptosis. | 4 |
| 24737586 | 2014 | DNA damage-inducible gene, UNC5A, functions as a tumor-suppressor in bladder cancer. | 9 |
| 24676280 | 2014 | The Fanconi anemia group C protein interacts with uncoordinated 5A and delays apoptosis. | 4 |
| 24737586 | 2014 | DNA damage-inducible gene, UNC5A, functions as a tumor-suppressor in bladder cancer. | 9 |
| 20372800 | 2010 | Identification of UNC5A as a novel transcriptional target of tumor suppressor p53 and a regulator of apoptosis. | 18 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20372800 | 2010 | Identification of UNC5A as a novel transcriptional target of tumor suppressor p53 and a regulator of apoptosis. | 18 |
Citation
Dessen P
UNC5A (unc-5 netrin receptor A)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43649/unc5a-(unc-5-netrin-receptor-a)
