PDLIM7 (PDZ and LIM domain 7)

2007-02-01 Affiliation

Identity

HGNC

PDLIM7

LOCATION

5q35.3

LOCUSID

9260

ALIAS

LMP1,LMP3

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9260
MIM: 605903
HGNC: 22958
Ensembl: ENSG00000196923

Variants:

dbSNP: 9260
ClinVar: 9260
TCGA: ENSG00000196923
COSMIC: PDLIM7

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000196923	ENST00000355572	Q9NR12
ENSG00000196923	ENST00000355841	Q9NR12
ENSG00000196923	ENST00000359895	Q9NR12
ENSG00000196923	ENST00000393546	H7BYK4
ENSG00000196923	ENST00000393551	Q9NR12
ENSG00000196923	ENST00000486828	Q9NR12
ENSG00000196923	ENST00000493815	Q9NR12
ENSG00000196923	ENST00000503827	H0Y8W6
ENSG00000196923	ENST00000505074	D6RH06
ENSG00000196923	ENST00000506161	D6RF83
ENSG00000196923	ENST00000506537	D6RAN1

Expression (GTEx)

100

200

300

400

500

600

700

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Developmental Biology	REACTOME	R-HSA-1266738
Axon guidance	REACTOME	R-HSA-422475
RET signaling	REACTOME	R-HSA-8853659

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
16611643	2006	LIM mineralization protein-1 potentiates bone morphogenetic protein responsiveness via a novel interaction with Smurf1 resulting in decreased ubiquitination of Smads.	25
21060154	2010	Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice.	22
22982077	2013	Lim mineralization protein is involved in the premature calvarial ossification in sporadic craniosynostoses.	16
25760809	2015	LMP-1 induces survivin expression to inhibit cell apoptosis through the NF-κB and PI3K/Akt signaling pathways in nasal NK/T-cell lymphoma.	14
27470516	2016	Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.	13
16803868	2006	Enigma interacts with adaptor protein with PH and SH2 domains to control insulin-induced actin cytoskeleton remodeling and glucose transporter 4 translocation.	12
18412141	2008	Epstein-Barr virus latent membrane protein 1 mediates serine 25 phosphorylation and nuclear entry of annexin A2 via PI-PLC-PKCalpha/PKCbeta pathway.	11
11874232	2002	Overexpressed LIM mineralization proteins do not require LIM domains to induce bone.	10
18395833	2008	Potential involvement of the interaction between insulin-like growth factor binding protein (IGFBP)-6 and LIM mineralization protein (LMP)-1 in regulating osteoblast differentiation.	9
21061915	2010	Early transcriptional events during osteogenic differentiation of human bone marrow stromal cells induced by Lim mineralization protein 3.	9

Citation

Dessen P

PDLIM7 (PDZ and LIM domain 7)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43666/pdlim7-(pdz-and-lim-domain-7)