Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2745
MIM: 600443
HGNC: 4330
Ensembl: ENSG00000173221
Variants:
dbSNP: 2745
ClinVar: 2745
TCGA: ENSG00000173221
COSMIC: GLRX
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism | REACTOME | R-HSA-1430728 |
| Metabolism of nucleotides | REACTOME | R-HSA-15869 |
| Synthesis and interconversion of nucleotide di- and triphosphates | REACTOME | R-HSA-499943 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37507364 | 2023 | Structural and functional fine mapping of cysteines in mammalian glutaredoxin reveal their differential oxidation susceptibility. | 1 |
| 37507364 | 2023 | Structural and functional fine mapping of cysteines in mammalian glutaredoxin reveal their differential oxidation susceptibility. | 1 |
| 35714567 | 2022 | Cytosolic glutaredoxin 1 is upregulated in AMD and controls retinal pigment epithelial cells proliferation via β-catenin. | 0 |
| 35714567 | 2022 | Cytosolic glutaredoxin 1 is upregulated in AMD and controls retinal pigment epithelial cells proliferation via β-catenin. | 0 |
| 33359085 | 2021 | Cellular S-denitrosylases: Potential role and interplay of Thioredoxin, TRP14, and Glutaredoxin systems in thiol-dependent protein denitrosylation. | 4 |
| 34587543 | 2021 | Glutaredoxin-1 levels in plasma can predict future events in patients with cardiovascular diseases. | 1 |
| 33359085 | 2021 | Cellular S-denitrosylases: Potential role and interplay of Thioredoxin, TRP14, and Glutaredoxin systems in thiol-dependent protein denitrosylation. | 4 |
| 34587543 | 2021 | Glutaredoxin-1 levels in plasma can predict future events in patients with cardiovascular diseases. | 1 |
| 31813265 | 2020 | Redox Regulation via Glutaredoxin-1 and Protein S-Glutathionylation. | 45 |
| 32481517 | 2020 | Activation of 3-Mercaptopyruvate Sulfurtransferase by Glutaredoxin Reducing System. | 2 |
| 32892658 | 2020 | Deficiency of Grx1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS. | 4 |
| 32948023 | 2020 | Role of Glutaredoxin-1 and Glutathionylation in Cardiovascular Diseases. | 19 |
| 33329553 | 2020 | Redox Regulator GLRX Is Associated With Tumor Immunity in Glioma. | 11 |
| 31813265 | 2020 | Redox Regulation via Glutaredoxin-1 and Protein S-Glutathionylation. | 45 |
| 32481517 | 2020 | Activation of 3-Mercaptopyruvate Sulfurtransferase by Glutaredoxin Reducing System. | 2 |
Citation
Dessen P
GLRX (glutaredoxin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43676/glrx-(glutaredoxin)
