Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4887
MIM: 162642
HGNC: 7957
Ensembl: ENSG00000185149
Variants:
dbSNP: 4887
ClinVar: 4887
TCGA: ENSG00000185149
COSMIC: NPY2R
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185149 | ENST00000329476 | P49146 |
| ENSG00000185149 | ENST00000506608 | P49146 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA255 | NPY | Gene | Pathway | associated | |||
| PA34090 | PYY | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36525977 | 2023 | Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. | 4 |
| 36525977 | 2023 | Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. | 4 |
| 31852985 | 2019 | Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients. | 17 |
| 31852985 | 2019 | Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients. | 17 |
| 28857123 | 2018 | Evaluation of a Role for NPY and NPY2R in the Pathogenesis of Obesity by Mutation and Copy Number Variation Analysis in Obese Children and Adolescents. | 6 |
| 30531682 | 2018 | The Association of CEP135 rs4865047 and NPY2R rs1902491 Single Nucleotide Polymorphisms (SNPs) with Rapid Progression of Proliferative Diabetic Retinopathy in Patients with Type 1 Diabetes Mellitus. | 3 |
| 28857123 | 2018 | Evaluation of a Role for NPY and NPY2R in the Pathogenesis of Obesity by Mutation and Copy Number Variation Analysis in Obese Children and Adolescents. | 6 |
| 30531682 | 2018 | The Association of CEP135 rs4865047 and NPY2R rs1902491 Single Nucleotide Polymorphisms (SNPs) with Rapid Progression of Proliferative Diabetic Retinopathy in Patients with Type 1 Diabetes Mellitus. | 3 |
| 27584037 | 2017 | Association between neuropeptide Y receptor Y2 promoter variant rs6857715 and major depressive disorder. | 6 |
| 27889920 | 2017 | Neuropeptide Y receptor 1 is expressed by B and T lymphocytes and mast cells in infantile haemangiomas. | 7 |
| 27584037 | 2017 | Association between neuropeptide Y receptor Y2 promoter variant rs6857715 and major depressive disorder. | 6 |
| 27889920 | 2017 | Neuropeptide Y receptor 1 is expressed by B and T lymphocytes and mast cells in infantile haemangiomas. | 7 |
| 25871004 | 2015 | Polymorphisms in neuropeptide genes and bone mineral density in Korean postmenopausal women. | 1 |
| 25924821 | 2015 | Unwinding of the C-Terminal Residues of Neuropeptide Y is critical for Y₂ Receptor Binding and Activation. | 33 |
| 25871004 | 2015 | Polymorphisms in neuropeptide genes and bone mineral density in Korean postmenopausal women. | 1 |
Citation
Dessen P
NPY2R (neuropeptide Y receptor Y2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43703/npy2r
