SLC2A1 (solute carrier family 2 member 1)

2007-02-01  

Identity

HGNC
SLC2A1
LOCATION
1p34.2
LOCUSID
6513
ALIAS
CSE,DYT17,DYT18,DYT9,EIG12,GLUT,GLUT-1,GLUT1,GLUT1DS,HTLVR,PED,SDCHCN
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6513
MIM: 138140
HGNC: 11005
Ensembl: ENSG00000117394

Variants:

dbSNP: 6513
ClinVar: 6513
TCGA: ENSG00000117394
COSMIC: SLC2A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117394ENST00000372500A6NL68
ENSG00000117394ENST00000426263P11166
ENSG00000117394ENST00000460369A0A1W2PQ59
ENSG00000117394ENST00000475162A0A0D9SG74
ENSG00000117394ENST00000630287A0A0D9SFK9
ENSG00000117394ENST00000669445A0A590UJ26

Expression (GTEx)

0
100
200
300
400
500
600
700
800
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Adipocytokine signaling pathwayKEGGko04920
Renal cell carcinomaKEGGko05211
Adipocytokine signaling pathwayKEGGhsa04920
Pathways in cancerKEGGhsa05200
Renal cell carcinomaKEGGhsa05211
Bile secretionKEGGko04976
Bile secretionKEGGhsa04976
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166
HIF-1 signaling pathwayKEGGhsa04066
Insulin secretionKEGGhsa04911
Thyroid hormone signaling pathwayKEGGhsa04919
Central carbon metabolism in cancerKEGGhsa05230
Central carbon metabolism in cancerKEGGko05230
Glucagon signaling pathwayKEGGhsa04922
Glucagon signaling pathwayKEGGko04922
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Hexose transportREACTOMER-HSA-189200
Glucose transportREACTOMER-HSA-70153
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Facilitative Na+-independent glucose transportersREACTOMER-HSA-428790
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Lactose synthesisREACTOMER-HSA-5653890
Integration of energy metabolismREACTOMER-HSA-163685
Regulation of insulin secretionREACTOMER-HSA-422356
Metabolism of vitamins and cofactorsREACTOMER-HSA-196854
Metabolism of water-soluble vitamins and cofactorsREACTOMER-HSA-196849
Vitamin C (ascorbate) metabolismREACTOMER-HSA-196836
Insulin resistanceKEGGhsa04931

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377735742024Gene expression of protein kinase AMP-activated catalytic subunit alpha 1 (PRKAA1), solute carrier family 2 member 1 (SLC2A1) and mechanistic target of rapamycin (MTOR) in metformin-treated type 2 diabetes patients with COVID-19: impact on inflammation markers.2
381769542024Inhibition of glycolysis and SIRT1/GLUT1 signaling ameliorates the apoptotic effect of Leptosidin in prostate cancer cells.0
382817112024GLUT1 mediates the release of HMGB1 from airway epithelial cells in mixed granulocytic asthma.0
382821512024BRIX1 promotes ribosome synthesis and enhances glycolysis by selected translation of GLUT1 in colorectal cancer.1
385140682024HNRNPC Regulates GLUT1/LDHA Pathway by Stabilizing FOXM1 mRNA to Promote the Progression and Aerobic Glycolysis of Multiple Myeloma.0
387449542024Ubiquitin-specific protease 54 regulates GLUT1-mediated aerobic glycolysis to inhibit lung adenocarcinoma progression by modifying p53 degradation.0
387770992024PURA and GLUT1: Sweet partners for brain health.0
388313212024GLUT1 promotes cell proliferation via binds and stabilizes phosphorylated EGFR in lung adenocarcinoma.0
377735742024Gene expression of protein kinase AMP-activated catalytic subunit alpha 1 (PRKAA1), solute carrier family 2 member 1 (SLC2A1) and mechanistic target of rapamycin (MTOR) in metformin-treated type 2 diabetes patients with COVID-19: impact on inflammation markers.2
381769542024Inhibition of glycolysis and SIRT1/GLUT1 signaling ameliorates the apoptotic effect of Leptosidin in prostate cancer cells.0
382817112024GLUT1 mediates the release of HMGB1 from airway epithelial cells in mixed granulocytic asthma.0
382821512024BRIX1 promotes ribosome synthesis and enhances glycolysis by selected translation of GLUT1 in colorectal cancer.1
385140682024HNRNPC Regulates GLUT1/LDHA Pathway by Stabilizing FOXM1 mRNA to Promote the Progression and Aerobic Glycolysis of Multiple Myeloma.0
387449542024Ubiquitin-specific protease 54 regulates GLUT1-mediated aerobic glycolysis to inhibit lung adenocarcinoma progression by modifying p53 degradation.0
387770992024PURA and GLUT1: Sweet partners for brain health.0

Citation

Dessen P

SLC2A1 (solute carrier family 2 member 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43725/slc2a1-(solute-carrier-family-2-member-1)