Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5734
MIM: 601586
HGNC: 9596
Ensembl: ENSG00000171522
Variants:
dbSNP: 5734
ClinVar: 5734
TCGA: ENSG00000171522
COSMIC: PTGER4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171522 | ENST00000302472 | P35408 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA446108 | Colorectal Neoplasms | Disease | ClinicalAnnotation | associated | PD | 23778325 | |
| PA448871 | celecoxib | Chemical | ClinicalAnnotation | associated | PD | 23778325 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38745046 | 2024 | EP4-induced mitochondrial localization and cell migration mediated by CALML6 in human oral squamous cell carcinoma. | 1 |
| 38745046 | 2024 | EP4-induced mitochondrial localization and cell migration mediated by CALML6 in human oral squamous cell carcinoma. | 1 |
| 37232020 | 2023 | Complementary roles of EP2 and EP4 receptors in malignant glioma. | 2 |
| 37670284 | 2023 | Association of PTGER4 and PRKAA1 genetic polymorphisms with gastric cancer. | 0 |
| 37232020 | 2023 | Complementary roles of EP2 and EP4 receptors in malignant glioma. | 2 |
| 37670284 | 2023 | Association of PTGER4 and PRKAA1 genetic polymorphisms with gastric cancer. | 0 |
| 34740924 | 2022 | Single-Cell Analysis Reveals EP4 as a Target for Restoring T-Cell Infiltration and Sensitizing Prostate Cancer to Immunotherapy. | 24 |
| 35549670 | 2022 | Nanomolar EP4 receptor potency and expression of eicosanoid-related enzymes in normal appearing colonic mucosa from patients with colorectal neoplasia. | 2 |
| 35914351 | 2022 | PARP14 regulates EP4 receptor expression in human colon cancer HCA-7 cells. | 1 |
| 36078128 | 2022 | The Prostaglandin E2 Receptor EP4 Promotes Vascular Neointimal Hyperplasia through Translational Control of Tenascin C via the cAPM/PKA/mTORC1/rpS6 Pathway. | 1 |
| 34740924 | 2022 | Single-Cell Analysis Reveals EP4 as a Target for Restoring T-Cell Infiltration and Sensitizing Prostate Cancer to Immunotherapy. | 24 |
| 35549670 | 2022 | Nanomolar EP4 receptor potency and expression of eicosanoid-related enzymes in normal appearing colonic mucosa from patients with colorectal neoplasia. | 2 |
| 35914351 | 2022 | PARP14 regulates EP4 receptor expression in human colon cancer HCA-7 cells. | 1 |
| 36078128 | 2022 | The Prostaglandin E2 Receptor EP4 Promotes Vascular Neointimal Hyperplasia through Translational Control of Tenascin C via the cAPM/PKA/mTORC1/rpS6 Pathway. | 1 |
| 33158942 | 2021 | Prostanoid Receptors of the EP(4)-Subtype Mediate Gene Expression Changes in Human Airway Epithelial Cells with Potential Anti-Inflammatory Activity. | 2 |
Citation
Dessen P
PTGER4 (prostaglandin E receptor 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43737/ptger4-(prostaglandin-e-receptor-4)
