Identity
HGNC
LOCATION
8q21.13
LOCUSID
ALIAS
BHLHb31,CHF2,HERP2,HESR1,HRT-1,NERP2,OAF1,hHRT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23462
MIM: 602953
HGNC: 4880
Ensembl: ENSG00000164683
Variants:
dbSNP: 23462
ClinVar: 23462
TCGA: ENSG00000164683
COSMIC: HEY1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164683 | ENST00000337919 | Q9Y5J3 |
| ENSG00000164683 | ENST00000354724 | Q9Y5J3 |
| ENSG00000164683 | ENST00000518733 | E5RHK6 |
| ENSG00000164683 | ENST00000523976 | B4DEI9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38166414 | 2024 | SUMOylation Fine-Tunes Endothelial HEY1 in the Regulation of Angiogenesis. | 2 |
| 38166414 | 2024 | SUMOylation Fine-Tunes Endothelial HEY1 in the Regulation of Angiogenesis. | 2 |
| 34002044 | 2022 | LncRNA MAGI2-AS3 inhibits tumor progression and angiogenesis by regulating ACY1 via interacting with transcription factor HEY1 in clear cell renal cell carcinoma. | 11 |
| 36396748 | 2022 | HEY1-mediated cisplatin resistance in lung adenocarcinoma via epithelial-mesenchymal transition. | 2 |
| 34002044 | 2022 | LncRNA MAGI2-AS3 inhibits tumor progression and angiogenesis by regulating ACY1 via interacting with transcription factor HEY1 in clear cell renal cell carcinoma. | 11 |
| 36396748 | 2022 | HEY1-mediated cisplatin resistance in lung adenocarcinoma via epithelial-mesenchymal transition. | 2 |
| 33236952 | 2021 | Long noncoding RNA LINC00982 upregulates CTSF expression to inhibit gastric cancer progression via the transcription factor HEY1. | 13 |
| 33491747 | 2021 | Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma. | 5 |
| 33236952 | 2021 | Long noncoding RNA LINC00982 upregulates CTSF expression to inhibit gastric cancer progression via the transcription factor HEY1. | 13 |
| 33491747 | 2021 | Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma. | 5 |
| 32293074 | 2020 | CAFs-derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling. | 18 |
| 32417395 | 2020 | IMPAD1 functions as mitochondrial electron transport inhibitor that prevents ROS production and promotes lung cancer metastasis through the AMPK-Notch1-HEY1 pathway. | 12 |
| 32712748 | 2020 | TWIST1 correlates with Notch signaling pathway to develop esophageal squamous cell carcinoma. | 4 |
| 32293074 | 2020 | CAFs-derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling. | 18 |
| 32417395 | 2020 | IMPAD1 functions as mitochondrial electron transport inhibitor that prevents ROS production and promotes lung cancer metastasis through the AMPK-Notch1-HEY1 pathway. | 12 |
Citation
Dessen P
HEY1 (hes related family bHLH transcription factor with YRPW motif 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43746
