Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 155
MIM: 109691
HGNC: 288
Ensembl: ENSG00000188778
Variants:
dbSNP: 155
ClinVar: 155
TCGA: ENSG00000188778
COSMIC: ADRB3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000188778 | ENST00000345060 | P13945 |
| ENSG00000188778 | ENST00000345060 | A8KAG8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406954 | Weight gain | Disease | ClinicalAnnotation | associated | PD | 19193342 | |
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation | associated | PD | 19193342 | |
| PA450688 | olanzapine | Chemical | ClinicalAnnotation | associated | PD | 19193342 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36831252 | 2023 | Alpha1A- and Beta3-Adrenoceptors Interplay in Adipose Multipotent Mesenchymal Stromal Cells: A Novel Mechanism of Obesity-Driven Hypertension. | 2 |
| 36863427 | 2023 | The β3 adrenoceptor in proliferative retinopathies: "Cinderella" steps out of its family shadow. | 5 |
| 36884028 | 2023 | β3AR-Dependent Brain-Derived Neurotrophic Factor (BDNF) Generation Limits Chronic Postischemic Heart Failure. | 8 |
| 36989522 | 2023 | Association of an ADRB3 Variant with Coronary Artery Disease Within the Chinese Han Population: Construction of a Predictive Nomogram Model. | 0 |
| 37628593 | 2023 | Effects of the Trp64Arg Polymorphism in the ADRB3 Gene on Body Composition, Cardiorespiratory Fitness, and Physical Activity in Healthy Adults. | 0 |
| 37938600 | 2023 | Urinary beta 3-adrenoceptor as a diagnostic biomarker for overactive bladder in women. | 1 |
| 36831252 | 2023 | Alpha1A- and Beta3-Adrenoceptors Interplay in Adipose Multipotent Mesenchymal Stromal Cells: A Novel Mechanism of Obesity-Driven Hypertension. | 2 |
| 36863427 | 2023 | The β3 adrenoceptor in proliferative retinopathies: "Cinderella" steps out of its family shadow. | 5 |
| 36884028 | 2023 | β3AR-Dependent Brain-Derived Neurotrophic Factor (BDNF) Generation Limits Chronic Postischemic Heart Failure. | 8 |
| 36989522 | 2023 | Association of an ADRB3 Variant with Coronary Artery Disease Within the Chinese Han Population: Construction of a Predictive Nomogram Model. | 0 |
| 37628593 | 2023 | Effects of the Trp64Arg Polymorphism in the ADRB3 Gene on Body Composition, Cardiorespiratory Fitness, and Physical Activity in Healthy Adults. | 0 |
| 37938600 | 2023 | Urinary beta 3-adrenoceptor as a diagnostic biomarker for overactive bladder in women. | 1 |
| 34967048 | 2022 | β3-Adrenoceptor, a novel player in the round-trip from neonatal diseases to cancer: Suggestive clues from embryo. | 9 |
| 35145073 | 2022 | ADRB3 induces mobilization and inhibits differentiation of both breast cancer cells and myeloid-derived suppressor cells. | 5 |
| 35947209 | 2022 | Development of a genetic risk score for obesity predisposition evaluation. | 5 |
Citation
Dessen P
ADRB3 (adrenoceptor beta 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43763/
